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Lichtalterung (Photoaging) der Haut: Was gibt es Neues?

Sun-damaged skin (photoaging): what is new?

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Zusammenfassung

Die Alterung der Haut resultiert aus dem Zusammenspiel genetischer und nichtgenetischer, sog. exposomaler Faktoren. Einer der wichtigsten exposomalen Faktoren ist die chronische, lebenslange Bestrahlung der Haut mit Sonnenlicht. Wichtig ist hierbei, dass die resultierende, sog. Lichtalterung der Haut nicht nur durch ultraviolette (UV) B- und A-Strahlung, sondern auch durch Wellenlängenbereiche jenseits des UV-Spektrums, nämlich durch das sichtbare, genauer das blaue Licht (400–440 nm), und durch die kurzwellige Infrarotstrahlung (IRA; 770–1200 nm) verursacht wird. In dieser Übersichtsarbeit fassen wir die hierfür relevante wissenschaftliche Evidenz zusammen und wie sich diese Erkenntnisse auf den täglichen Lichtschutz auswirken. Zudem verdeutlichen wir die klinischen Konsequenzen, die das Konzept des Hautalterungsexposoms für die dermatologische Praxis hat und die sich u. a. aus der Interaktion des Sonnenlichts mit anderen exposomalen Faktoren ergibt.

Abstract

Skin aging results from the interaction of genetic and nongenetic so-called exposomal, factors. Among the exposomal factors, chronic, life-long exposure to sunlight is of eminent importance for the development of skin aging characteristics. Importantly, photoaging of human skin is not only caused by ultraviolet (UV) B and A radiation, but is also the consequence of exposure to wavelengths beyond the UV spectrum. These include visible, i.e. blue light (400–440 nm) as well as the short part of infrared radiation, i.e. IRA (760–1200 nm). Here we summarize the scientific evidence supporting these conclusions and emphasize the resulting consequences for daily photoprotection of human skin. We also explain the clinical significance of the concept that is offered by the skin aging exposome, which e.g. takes into account the fact that sunlight interacts with other exposomal factors and that this interaction is important for photoaging of the skin.

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Authors and Affiliations

  1. IUF – Leibniz-Institut für umweltmedizinische Forschung, Auf’m Hennekamp 50, 40225, Düsseldorf, Deutschland

    J. Krutmann

  2. Klinik und Poliklinik für Dermatologie, UKR – Universitätsklinikum Regensburg, Regensburg, Deutschland

    M. Berneburg

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  1. J. Krutmann
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Correspondence to J. Krutmann.

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Interessenkonflikt

J. Krutmann und M. Berneburg geben an, dass kein Interessenkonflikt besteht.

Für diesen Beitrag wurden von den Autoren keine Studien an Menschen oder Tieren durchgeführt. Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.

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Krutmann, J., Berneburg, M. Lichtalterung (Photoaging) der Haut: Was gibt es Neues?. Hautarzt 72, 2–5 (2021). https://doi.org/10.1007/s00105-020-04747-4

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  • DOI: https://doi.org/10.1007/s00105-020-04747-4

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