Abstract
A water solubility of 5.5 (±0.22) μg/L for di(2-ethylhexyl) adipate (DEHA) was measured using the slow-stir method. This value is consistent with computer estimations and over two orders of magnitude lower than that previously determined using the shake-flask method. We performed a 21-day chronic Daphnia magna limit test at an average exposure of 4.4 μg/L in laboratory diluent water to avoid insoluble test material and avoid physical entrapment. One hundred percent of the DEHA-treated organisms survived compared to 90% survival in both the controls and solvent controls. Mean neonate reproduction was 152, 137, and 148 and mean dry weight per surviving female was 0.804, 0.779, and 0.742 mg in the DEHA treatment, control, and solvent control, respectively. No adverse effects were observed.
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Acknowledgments
T. Primus, T. Buettgenbach, M. Goodall, D. Griffin and J. Johnson at the National Wildlife Research Center, USDA, Fort Collins, CO, USA developed the analytical method for DEHA and performed the analysis. D. Peterson and D. Letinski provided useful guidance on the design of the experiments. The American Chemistry Council, Phthalate Ester Panel provided funding for this study.
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Robillard, K., DuFresne, D., Gorsuch, J. et al. Aqueous Solubility and Daphnia magna Chronic Toxicity of Di(2-ethylhexyl) Adipate. Bull Environ Contam Toxicol 80, 539–543 (2008). https://doi.org/10.1007/s00128-008-9399-4
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DOI: https://doi.org/10.1007/s00128-008-9399-4