References
WHO Ebola Response Team (2014) Ebola virus disease in West Africa—the first 9 months of the epidemic and forward projections. N Engl J Med 371:1481–1495
Tattevin P, Durante E, Massaquoi M (2014) Does this patient have Ebola virus disease? Intensive Care Med 40:1738–1741
Bah EI, Lamah MC, Fletcher T, Jacob ST, Brett-Major DM, Sall AA, Shindo N, Fischer WA, Lamontagne F, Saliou SM, Bausch DG, Moumi B, Jagatic T, Sprecher A, Lawler JV, Mayet T, Jacquerioz FA, Baggi MaFM, Vallenas C, Clement C, Mardel S, Faye O, Faye O, Soropogui B, Magassouba N, Koivogui L, Pinto R, Fowler RA (2014) Clinical presentation of patients with Ebola virus disease in Conakry, Guinea. N Engl J Med. doi:10.1056/NEJMoa1411249
Chertow DS, Kleine C, Edwards JK, Scaini R, Giuliani R, Sprecher A (2014) Ebola virus disease in West Africa—clinical manifestations and management. N Engl J Med. doi:10.1056/NEJMp1413084
Fisher-Hoch SP, Platt GS, Neild GH, Southee T, Baskerville A, Raymond RT, Lloyd G, Simpson DI (1985) Pathophysiology of shock and hemorrhage in a fulminating viral infection (Ebola). J Infect Dis 152:887–894
Fowler RA, Fletcher T, Fischer WA, Lamontagne F, Jacob S, Brett-Major D, Lawler JV, Jacquerioz FA, Houlihan C, O’Dempsey T, Ferri M, Adachi T, Lamah MC, Bah EI, Mayet T, Schieffelin J, McLellan SL, Senga M, Kato Y, Clement C, Mardel S, Vallenas Bejar De Villar RC, Shindo N, Bausch D (2014) Caring for critically ill patients with ebola virus disease. Perspectives from West Africa. Am J Respir Crit Care Med 190:733–737
Kreuels B, Wichmann D, Emmerich P, Schmidt-Chanasit J, de HG, Kluge S, Sow A, Renne T, Gunther S, Lohse AW, Addo MM, Schmiedel S (2014) A case of severe Ebola virus infection complicated by Gram-negative septicemia. N Engl J Med. doi:10.1056/NEJMoa1411677
Schieffelin JS, Shaffer JG, Goba A, Gbakie M, Gire SK, Colubri A, Sealfon RSG, Kanneh L, Moigboi A, Momoh M, Fullah M, Moses LM, Brown BL, Andersen KG, Winnicki S, Schaffner SF, Park DJ, Yozwiak NL, Jiang PP, Kargbo D, Jalloh S, Fonnie M, Sinnah V, French I, Kovoma A, Kamara FK, Tucker V, Konuwa E, Sellu J, Mustapha I, Foday M, Yillah M, Kanneh F, Saffa S, Massally JLB, Boisen ML, Branco LM, Vandi MA, Grant DS, Happi C, Gevao SM, Fletcher TE, Fowler RA, Bausch DG, Sabeti PC, Khan SH, Garry RF (2014) Clinical illness and outcomes in patients with Ebola in Sierra Leone. N Engl J Med. doi:10.1056/NEJMoa1411680
Perner A, Junttila E, Haney M, Hreinsson K, Kvale R, Vandvik PO, Moller MH (2014) Scandinavian clinical practice guideline on choice of fluid in resuscitation of critically ill patients with acute circulatory failure. Acta Anaesthesiol Scand. doi:10.1111/aas.12429
Holst LB, Haase N, Wetterslev J, Wernerman J, Guttormsen AB, Karlsson S, Johansson PI, Aneman A, Vang ML, Winding R, Nebrich L, Nibro HL, Rasmussen BS, Lauridsen JR, Nielsen JS, Oldner A, Pettila V, Cronhjort MB, Andersen LH, Pedersen UG, Reiter N, Wiis J, White JO, Russell L, Thornberg KJ, Hjortrup PB, Muller RG, Moller MH, Steensen M, Tjader I, Kilsand K, Odeberg-Wernerman S, Sjobo B, Bundgaard H, Thyo MA, Lodahl D, Maerkedahl R, Albeck C, Illum D, Kruse M, Winkel P, Perner A (2014) Lower versus higher hemoglobin threshold for transfusion in septic shock. N Engl J Med 371:1381–1391
Yealy DM, Kellum JA, Huang DT, Barnato AE, Weissfeld LA, Pike F, Terndrup T, Wang HE, Hou PC, LoVecchio F, Filbin MR, Shapiro NI, Angus DC (2014) A randomized trial of protocol-based care for early septic shock. N Engl J Med 370:1683–1693
Peake SL, Delaney A, Bailey M, Bellomo R, Cameron PA, Cooper DJ, Higgins AM, Holdgate A, Howe BD, Webb SA, Williams P (2014) Goal-directed resuscitation for patients with early septic shock. N Engl J Med 371:1496–1506
Maitland K, Kiguli S, Opoka RO, Engoru C, Olupot-Olupot P, Akech SO, Nyeko R, Mtove G, Reyburn H, Lang T, Brent B, Evans JA, Tibenderana JK, Crawley J, Russell EC, Levin M, Babiker AG, Gibb DM (2011) Mortality after fluid bolus in African children with severe infection. N Engl J Med 364:2483–2495
Fletcher T, Fowler R, Beeching N (2014) Understanding organ dysfunction in Ebola virus disease. Intensive Care Med 40:1936–1939. doi:10.1007/s00134-014-3515-1
Conflicts of interest
The ICU at Rigshospitalet, where AP is head of research, receives research funds from Fresenius Kabi and CSL Behring. The other authors have no conflicts of interests.
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Perner, A., Fowler, R.A., Bellomo, R. et al. Ebola care and research protocols. Intensive Care Med 41, 111–114 (2015). https://doi.org/10.1007/s00134-014-3568-1
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DOI: https://doi.org/10.1007/s00134-014-3568-1