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Dilation and surgical management in vaginal agenesis: a systematic review

  • Review Article
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Abstract

Introduction

The management of vaginal agenesis is currently determined by geographical location and surgeon preference. The optimal treatment is unknown and the majority of articles on technique and outcome focus on personal case series with little standardisation of reporting and follow-up.

Methods

Six thousand six hundred and ninety-one articles concerning the management of vaginal agenesis were systematically reviewed, with 162 fitting the inclusion criteria.

Results

Only one randomised control trial was included with the remaining articles made up of case series or case reports. The bowel vaginoplasty method was most commonly reported historically with 945 patients and 45 articles included. The Vecchietti procedure had the shortest operative time, but the highest number of urological injuries (2.1 %). The split thickness procedure had the highest infection rate (4.2 %) and re-operation rate (7.84 %).

Conclusion

Overall, the conservative method using dilation had the fewest complications, with an average vaginal length of 6.65 cm (± 1.39 cm). However, with an operative procedure full consent is imperative, as is an understanding of the need for postoperative dilation with the majority of techniques.

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References

  1. Capraro VJ, Gallego MB (1976) Vaginal agenesis. Am J Obstet Gynecol 124(1):98–107

    CAS  PubMed  Google Scholar 

  2. Kimberley N, Hudson JM, Grover SR (2012) Vaginal agenesis, the hymen and associated anomalies. J Pediatr Adolesc Gynecol 25(1):54–58

    CAS  PubMed  Google Scholar 

  3. Mayer CAJ (1829) Über Verdoppelungen des Uterus und ihre Arten, nebst Bemerkungen über Hasenscharte und Wolfsrachen. J Chir Auger 13:525–565

    Google Scholar 

  4. Rokitansky K (1838) Über die sogenannten Verdoppelungen des Uterus. Med Jahrb Ost Staat 26:39–77

    Google Scholar 

  5. Küster H (1910) Uterus bipartitus solidus rudimentarius cum vagina solida. Z Geb Gyn 67:692

    Google Scholar 

  6. Hauser GA, Schreiner WE (1961) Mayer-Rokitansky-Küster syndrome: rudimentary solid bipartite uterus with solid vagina. Schweiz Med Wochenschr 91:381–384

    CAS  PubMed  Google Scholar 

  7. Merriam–Webster Dictionary (2013). http://www.merriam-webster.com/dictionary/. Accessed 15 June 2013

  8. Goldwyn RM (1977) History of attempts to form a vagina. Plast Reconstr Surg 59(3):319–329

    CAS  PubMed  Google Scholar 

  9. Abbe R (1898) New method of creating a vagina in a case of congenital absence. Med Rec 54:836–838

    Google Scholar 

  10. Baldwin JF (1904) XIV. The formation of an artificial vagina by intestinal transplantation. Ann Surg 40(3):398–403

    CAS  PubMed Central  PubMed  Google Scholar 

  11. Frank RT (1938) The formation of an artificial vagina without operation. Am J Obstet Gynecol 35:1035

    Google Scholar 

  12. Banister JB, McIndoe AH (1938) Congenital absence of the vagina, treated by means of an indwelling skin-graft. Proc R Soc Med 31(9):1055–1056

    CAS  PubMed Central  PubMed  Google Scholar 

  13. Sheares BH (1960) Congenital atresia of the vagina: a new technique for tunnelling the space between bladder and rectum and construction of the new vagina by a modified Wharton technique. J Obstet Gynaecol Br Emp 67:24–31

    CAS  PubMed  Google Scholar 

  14. Creatsas G, Deligeoroglou E, Makrakis E, Kontoravdis A, Papadimitriou L (2001) Creation of a neovagina following Williams vaginoplasty and the Creatsas modification in 111 patients with Mayer-Rokitansky-Kuster-Hauser syndrome. Fertil Steril 76(5):1036–1040

    CAS  PubMed  Google Scholar 

  15. Vecchietti G (1965) [Creation of an artificial vagina in Rokitansky-Kuster-Hauser syndrome]. Curr Newsl Obstet Gynecol 11(2):131–147 Article in Italian

    CAS  Google Scholar 

  16. D’Alberton A, Santi F (1972) Formation of a neovagina by coitus. Obstet Gynecol 40(5):763–764

    PubMed  Google Scholar 

  17. Wharton LR (1938) A simple method of constructing a vagina: report of four cases. Ann Surg 107(5):842–854

    CAS  PubMed Central  PubMed  Google Scholar 

  18. Giraldo F, Gaspar D, Gonzalez C, Bengoechea M, Ferron M (1994) Treatment of vaginal agenesis with vulvoperineal fasciocutaneous flaps. Plast Reconstr Surg 93(1):131–138, discussion 9–40

    CAS  PubMed  Google Scholar 

  19. Cao L, Wang Y, Li Y, Xu H (2013) Prospective randomized comparison of laparoscopic peritoneal vaginoplasty with laparoscopic sigmoid vaginoplasty for treating congenital vaginal agenesis. Int Urogynecol J 24:1173–1179

    PubMed  Google Scholar 

  20. Fedele L, Bianchi S, Frontino G, Berlanda N, Montefusco S, Borruto F (2008) Laparoscopically assisted uterovestibular anastomosis in patients with uterine cervix atresia and vaginal aplasia. Fertil Steril 89(1):212–216

    PubMed  Google Scholar 

  21. Brucker SY, Rall K, Campo R, Oppelt P, Isaacson K (2011) Treatment of congenital malformations. Semin Reprod Med 29(2):101–112

    PubMed  Google Scholar 

  22. Carrard C, Chevret-Measson M, Lunel A, Raudrant D (2012) Sexuality after sigmoid vaginoplasty in patients with Mayer-Rokitansky-Kuster-Hauser syndrome. Fertil Steril 97(3):691–696

    PubMed  Google Scholar 

  23. Rajimwale A, Furness PD III, Brant WO, Koyle MA (2004) Vaginal construction using sigmoid colon in children and young adults. BJU Int 94(1):115–119

    PubMed  Google Scholar 

  24. Bean EJ, Mazur T, Robinson AD (2009) Mayer-Rokitansky-Kuster-Hauser syndrome: sexuality, psychological effects, and quality of life. J Pediatr Adolesc Gynecol 22(6):339–346

    CAS  PubMed  Google Scholar 

  25. Cai B, Zhang JR, Xi XW, Yan Q, Wan XP (2007) Laparoscopically assisted sigmoid colon vaginoplasty in women with Mayer-Rokitansky-Kuster-Hauser syndrome: feasibility and short-term results. BJOG Int J Obstet Gynaecol 114(12):1486–1492

    CAS  Google Scholar 

  26. Communal P (2003) Sexuality after sigmoid colpopoiesis in patients with Mayer Rokitansky Kuster Hauser Syndrome. Fertil Steril 80(3):600–606

    PubMed  Google Scholar 

  27. Darai E, Toullalan O, Besse O, Potiron L, Delga P (2003) Anatomic and functional results of laparoscopic-perineal neovagina construction by sigmoid colpoplasty in women with Rokitansky’s syndrome. Hum Reprod 18(11):2454–2459

    PubMed  Google Scholar 

  28. Del Rossi C, Attanasio A, Del Curto S, D’Agostino S, De Castro R (2003) Treatment of vaginal atresia at a missionary hospital in Bangladesh: results and followup of 20 cases. J Urol 170(3):864–866

    PubMed  Google Scholar 

  29. Djordjevic ML, Stanojevic DS, Bizic MR (2011) Rectosigmoid vaginoplasty: clinical experience and outcomes in 86 cases. J Sex Med 8(12):3487–3494

    PubMed  Google Scholar 

  30. Ekinci S, Karnak I, Ciftci AO, Senocak ME, Tanyel FC, Buyukpamukcu N (2006) Sigmoid colon vaginoplasty in children. Eur J Pediatr Surg 16(3):182–187

    CAS  PubMed  Google Scholar 

  31. El-Sayed HM, El-Lamie IK, Ibrahim AM, El-Lamie KI (2007) Vaginal reconstruction with sigmoid colon in vaginal agenesis. Int Urogynecol J Pelvic Floor Dysfunct 18(9):1043–1047

    PubMed  Google Scholar 

  32. Filipas D, Black P, Hohenfellner R (2000) The use of isolated caecal bowel segment in complicated vaginal reconstruction. BJU Int 85(6):715–719

    CAS  PubMed  Google Scholar 

  33. Franz RC (1996) Sigmoid colon vaginoplasty: a modified method. Br J Obstet Gynaecol 103(11):1148–1155

    CAS  PubMed  Google Scholar 

  34. Freitas Filho LG, Carnevale J, Melo CE, Laks M, Miranda EG (2001) Sigmoid reconfigured vaginal construction in children. J Urol 166(4):1426–1428

    CAS  PubMed  Google Scholar 

  35. Freundt I, Toolenaar TA, Huikeshoven FJ, Drogendijk AC, Jeekel H (1992) A modified technique to create a neovagina with an isolated segment of sigmoid colon. Surg Gynecol Obstet 174(1):11–16

    CAS  PubMed  Google Scholar 

  36. Freundt I, Toolenaar TA, Huikeshoven FJ, Jeekel H, Drogendijk AC (1993) Long-term psychosexual and psychosocial performance of patients with a sigmoid neovagina. Am J Obstet Gynecol 169(5):1210–1214

    CAS  PubMed  Google Scholar 

  37. Gatti C, Del Rossi C, Lombardi L, Caravaggi F, Casolari E, Casadio G (2010) Sexuality and psychosocial functioning in young women after colovaginoplasty. J Urol 184 [4 Suppl]:1799–1803

    PubMed  Google Scholar 

  38. Graziano K, Teitelbaum DH, Hirschl RB, Coran AG (2002) Vaginal reconstruction for ambiguous genitalia and congenital absence of the vagina: a 27-year experience. J Pediatr Surg 37(7):955–960

    PubMed  Google Scholar 

  39. Hensle TW, Reiley EA (1998) Vaginal replacement in children and young adults. J Urol 159(3):1035–1038

    CAS  PubMed  Google Scholar 

  40. Hensle TW, Shabsigh A, Shabsigh R, Reiley EA, Meyer-Bahlburg HFL (2006) Sexual function following bowel vaginoplasty. J Urol 175(6):2283–2286

    PubMed  Google Scholar 

  41. Imparato E, Alfei A, Aspesi G, Meus AL, Spinillo A (2007) Long-term results of sigmoid vaginoplasty in a consecutive series of 62 patients. Int Urogynecol J Pelvic Floor Dysfunct 18(12):1465–1469

    PubMed  Google Scholar 

  42. Kapoor R, Sharma DK, Singh KJ, Suri A, Singh P, Chaudhary H et al (2006) Sigmoid vaginoplasty: long-term results. Urology 67(6):1212–1215

    PubMed  Google Scholar 

  43. Karateke A, Gurbuz A, Haliloglu B, Kabaca C, Koksal N (2006) Intestinal vaginoplasty: is it optimal treatment of vaginal agenesis? A pilot study. Surgical method of sigmoid colon vaginoplasty in vaginal agenesis. Int Urogynecol J Pelvic Floor Dysfunct 17(1):40–45

    PubMed  Google Scholar 

  44. Karateke A, Haliloglu B, Parlak O, Cam C, Coksuer H (2010) Intestinal vaginoplasty: 7 years’ experience of a tertiary center. Fertil Steril 94(6):2312–2315

    PubMed  Google Scholar 

  45. Khen-Dunlop N, Lortat-Jacob S, Thibaud E, Clement-Ziza M, Lyonnet S, Nihoul-Fekete C (2007) Rokitansky syndrome: clinical experience and results of sigmoid vaginoplasty in 23 young girls. J Urol 177(3):1107–1111

    PubMed  Google Scholar 

  46. Kwun Kim S, Hoon Park J, Cheol Lee K, Min Park J, Tae Kim J, Chan Kim M (2003) Long-term results in patients after rectosigmoid vaginoplasty. Plast Reconstr Surg 112(1):143–151

    PubMed  Google Scholar 

  47. Lenaghan R, Wilson N, Lucas CE, Ledgerwood AM (1997) The role of rectosigmoid neocolporrhaphy. Surgery 122(4):856–860

    CAS  PubMed  Google Scholar 

  48. Lima M, Ruggeri G, Randi B, Domini M, Gargano T, La Pergola E et al (2010) Vaginal replacement in the pediatric age group: a 34-year experience of intestinal vaginoplasty in children and young girls. J Pediatr Surg 45(10):2087–2091

    PubMed  Google Scholar 

  49. Louis-Sylvestre C, Haddad B, Paniel BJ (1997) Creation of a sigmoid neovagina: technique and results in 16 cases. Eur J Obstet Gynecol Reprod Biol 75(2):225–229

    CAS  PubMed  Google Scholar 

  50. Mane SB, Shastri P, Dhende NP, Obaidah A, Acharya H, Reddy S et al (2010) Our 10-year experience of variable Mullerian anomalies and its management. Pediatr Surg Int 26(8):795–800

    PubMed  Google Scholar 

  51. Martinez-Mora J, Isnard R, Castellvi A, Lopez Ortiz P (1992) Neovagina in vaginal agenesis: surgical methods and long-term results. J Pediatr Surg 27(1):10–14

    CAS  PubMed  Google Scholar 

  52. Matsui H, Seki K, Sekiya S (1999) Prolapse of the neovagina in Mayer-Rokitansky-Kuster-Hauser syndrome. A case report. J Reprod Med 44(6):548–550

    CAS  PubMed  Google Scholar 

  53. Munkarah A, Malone JM Jr, Budev HD, Evans TN (1994) Mucinous adenocarcinoma arising in a neovagina. Gynecol Oncol 52(2):272–275

    CAS  PubMed  Google Scholar 

  54. Nowier A, Esmat M, Hamza RT (2012) Surgical and functional outcomes of sigmoid vaginoplasty among patients with variants of disorders of sex development. Int Braz J Urol 38(3):380–386, discussions 7–8

    CAS  PubMed  Google Scholar 

  55. O’Connor JL, DeMarco RT, Pope JC, Adams MC, Brock JW 3rd (2004) Bowel vaginoplasty in children: a retrospective review. J Pediatr Surg 39(8):1205–1208

    PubMed  Google Scholar 

  56. Ozkan O, Akar ME, Ozkan O, Colak T, Kayacan N, Taskin O (2010) The use of vascularized jejunum flap for vaginal reconstruction: clinical experience and results in 22 patients. Microsurgery 30(2):125–131

    PubMed  Google Scholar 

  57. Parsons JK, Gearhart SL, Gearhart JP (2002) Vaginal reconstruction utilizing sigmoid colon: complications and long-term results. J Pediatr Surg 37(4):629–633

    PubMed  Google Scholar 

  58. Rawat J, Ahmed I, Pandey A, Khan TR, Singh S, Wakhlu A et al (2010) Vaginal agenesis: experience with sigmoid colon neovaginoplasty. J Indian Assoc Pediatr Surg 15(1):19–22

    PubMed Central  PubMed  Google Scholar 

  59. Syed HA, Malone PS, Hitchcock RJ (2001) Diversion colitis in children with colovaginoplasty. BJU Int 87(9):857–860

    CAS  PubMed  Google Scholar 

  60. Tillem SM, Stock JA, Hanna MK (1998) Vaginal construction in children. J Urol 160(1):186–190

    CAS  PubMed  Google Scholar 

  61. Urbanowicz W, Starzyk J, Sulislawski J (2004) Laparoscopic vaginal reconstruction using a sigmoid colon segment: a preliminary report. J Urol 171(6):2632–2635

    CAS  PubMed  Google Scholar 

  62. Wu JX, Li B, Li WZ, Jiang YG, Liang JX, Zhong CX (2009) Laparoscopic vaginal reconstruction using an ileal segment. Int J Gynaecol Obstet Off Organ Int Fed Gynaecol Obstet 107(3):258–261

    Google Scholar 

  63. Wu JX, Li B, Liu T, Li WZ, Jiang YG, Liang JX et al (2009) Eighty-six cases of laparoscopic vaginoplasty using an ileal segment. Chin Med J 122(16):1862–1866

    PubMed  Google Scholar 

  64. Yokomizo R, Murakami T, Naitou H, Yamada A (2002) Treatment for prolapse of the sigmoid neovagina in Mayer-Rokitansky-Kuster-Hauser syndrome. Obstet Gynecol 100(5 Pt 2):1085–1087

    PubMed  Google Scholar 

  65. Zhao YZ, Jiang H, Liu AT, Jiang DZ, Zhu XH, Qiu M et al (2011) Laparoscope-assisted creation of a neovagina using pedicled ileum segment transfer. World J Surg 35(10):2315–2322

    PubMed  Google Scholar 

  66. Zhong CX, Wu JX, Liang JX, Wu QH (2012) Laparoscopic and gasless laparoscopic sigmoid colon vaginoplasty in women with vaginal agenesis. Chin Med J 125(2):203–208

    PubMed  Google Scholar 

  67. Erman Akar M, Ozkan O, Ozkan O, Colak T, Gecici O (2013) Sexual function and long-term results following vaginal reconstruction with free vascular jejunal flap. J Sex Med

  68. Ajmal S, Yusuf K (2010) Vaginoplasty with bilateral islanded pudendal thigh flaps. J Ayub Med Coll Abbottabad JAMC 22(1):1–6

    Google Scholar 

  69. Akn S (2004) Experience with neovaginal construction using the full-thickness skin graft in vaginal agenesis. Ann Plast Surg 52(4):391–396, discussion 7

    PubMed  Google Scholar 

  70. Ang Z, Qun Q, Peirong Y, Fei LZ, Lin Z, Wei LW et al (2009) Refined DIEP flap technique for vaginal reconstruction. Urology 74(1):197–201

    PubMed  Google Scholar 

  71. Borkowski A, Czaplicki M, Dobronski P (2008) Twenty years of experience with Krzeski’s cystovaginoplasty for vaginal agenesis in Mayer-Rokitansky-Kuster-Hauser syndrome: anatomical, histological, cytological and functional results. BJU Int 101(11):1433–1440

    PubMed  Google Scholar 

  72. Coulon C, Orazi G, Nayama M, Cosson M (2005) Prolapse of neovagina created with labia minora: a case report. Int Urogynecol J Pelvic Floor Dysfunct 16(5):409–411

    PubMed  Google Scholar 

  73. Giraldo F (2003) Cutaneous neovaginoplasty using the Malaga flap (vulvoperineal fasciocutaneous flap): a 12-year follow-up. Plast Reconstr Surg 111(3):1249–1256

    PubMed  Google Scholar 

  74. Giraldo F, Solano A, Mora MJ, Smith V (1998) Hair growth in the vagina after reconstruction with pudendal thigh flaps in congenital vaginal agenesis. Plast Reconstr Surg 102(3):924–925

    CAS  PubMed  Google Scholar 

  75. Purushothaman V (2005) Horse shoe flap vaginoplasty–a new technique of vaginal reconstruction with labia minora flaps for primary vaginal agenesis. Br J Plast Surg 58(7):934–939

    CAS  PubMed  Google Scholar 

  76. Tahmeedullah, Khan AT, Obaidullah (2003) Functional outcome of Horton’s vaginoplasty. J Coll Physicians Surg Pak 13(10):596–599

    CAS  PubMed  Google Scholar 

  77. Tosun Z, Hoşnuter M, Savacı N, Çapar M, Şentürk S (2004) Experience with vaginoplasty. Scand J Plast Reconstr Surg Hand Surg 38(1):27–31

    PubMed  Google Scholar 

  78. Weiwei L, Zhifei L, Ang Z, Lin Z, Dan L, Qun Q (2009) Vaginal reconstruction with the muscle-sparing vertical rectus abdominis myocutaneous flap. J Plast Reconstr Aesthet Surg JPRAS 62(3):335–340

    Google Scholar 

  79. Selcuk CT, Evsen MS, Ozalp B, Durgun M (2013) Reconstruction of vaginal agenesis with pudendal thigh flaps thinned with liposuction. J Plast Reconstr Aesthet Surg JPRAS 66(9):e246–e250

    Google Scholar 

  80. Borruto F (1992) Mayer-Rokitansky-Kuster Syndrome: Vecchietti’s personal series. Clin Exp Obstet Gynecol 19(4):273–274

    CAS  PubMed  Google Scholar 

  81. Borruto F, Camoglio FS, Zampieri N, Fedele L (2007) The laparoscopic Vecchietti technique for vaginal agenesis. Int J Gynaecol Obstet Off Organ Int Fed Gynaecol Obstet 98:15–19

    CAS  Google Scholar 

  82. Borruto F, Chasen ST, Chervenak FA, Fedele L (1999) The Vecchietti procedure for surgical treatment of vaginal agenesis: comparison of laparoscopy and laparotomy. Int J Gynaecol Obstet Off Organ Int Fed Gynaecol Obstet 64(2):153–158

    CAS  Google Scholar 

  83. Brucker SY, Gegusch M, Zubke W, Rall K, Gauwerky JF, Wallwiener D (2008) Neovagina creation in vaginal agenesis: development of a new laparoscopic Vecchietti-based procedure and optimized instruments in a prospective comparative interventional study in 101 patients. Fertil Steril 90(5):1940–1952

    PubMed  Google Scholar 

  84. Brun JL, Belleannee G, Grafeille N, Aslan AF, Brun GH (2002) Long-term results after neovagina creation in Mayer-Rokitanski-Kuster-Hauser syndrome by Vecchietti’s operation. Eur J Obstet Gynecol Reprod Biol 103(2):168–172

    PubMed  Google Scholar 

  85. Csermely T, Halvax L, Sarkany A, Jeges S, Vizer M, Bozsa S et al (2011) Sexual function after modified laparoscopic Vecchietti’s vaginoplasty. J Pediatr Adolesc Gynecol 24(3):147–152

    PubMed  Google Scholar 

  86. El Saman AM, Fathalla MM, Nasr AM, Youssef MA (2007) Laparoscopically assisted balloon vaginoplasty for management of vaginal aplasia. Int J Gynaecol Obstet Off Organ Int Fed Gynaecol Obstet 98(2):134–137

    Google Scholar 

  87. El Saman AM, Fathalla MM, Zakherah MS, Shaaban OM, Nasr A (2009) Modified balloon vaginoplasty: the fastest way to create a natural: minor changes in technique eliminate the need for customized instruments. Am J Obstet Gynecol 201(5):546.e1–546.e5

    Google Scholar 

  88. El Saman AM, Zakherah MS, Nasr AM, Fathalla MM (2009) Distension versus traction in laparoscopically assisted balloon vaginoplasty for management of vaginal aplasia. Int J Gynaecol Obstet 104(1):72–73

    PubMed  Google Scholar 

  89. Fedele L, Bianchi S, Berlanda N, Fontana E, Raffaelli R, Bulfoni A et al (2006) Neovaginal mucosa after Vecchietti’s laparoscopic operation for Rokitansky syndrome: structural and ultrastructural study. Am J Obstet Gynecol 195(1):56–61

    PubMed  Google Scholar 

  90. Fedele L, Bianchi S, Frontino G, Fontana E, Restelli E, Bruni V (2008) The laparoscopic Vecchietti’s modified technique in Rokitansky syndrome: anatomic, functional, and sexual long-term results. Am J Obstet Gynecol 198(4):377.e1–377.e6

    Google Scholar 

  91. Fedele L, Bianchi S, Zanconato G, Raffaelli R (2000) Laparoscopic creation of a neovagina in patients with Rokitansky syndrome: analysis of 52 cases. Fertil Steril 74(2):384–389

    CAS  PubMed  Google Scholar 

  92. Fedele L, Frontino G, Restelli E, Ciappina N, Motta F, Bianchi P (2010) Creation of a neovagina by Davydov’s laparoscopic modified technique in patients with Rokitansky syndrome. Am J Obstet Gynecol 202(1):33.e1–33.e6

    Google Scholar 

  93. Folgueira G, Perez-Medina T, Martinez-Cortes L, Martinez-Lara A, Gomez B, Izquierdo J et al (2006) Laparoscopic creation of a neovagina in Mayer-Rokitansky-Kuster-Hauser syndrome by modified Vecchietti’s procedure. Eur J Obstet Gynecol Reprod Biol 127(2):240–243

    PubMed  Google Scholar 

  94. Kaloo PD, Cooper MJ, Reid G (2006) A prospective multi-centre study of major complications experienced during excisional laparoscopic surgery for endometriosis. Eur J Obstet Gynecol Reprod Biol 124(1):98–100

    PubMed  Google Scholar 

  95. Khater E, Fatthy H (1999) Laparoscopic Vecchietti vaginoplasty. J Am Assoc Gynecol Laparosc 6(2):179–182

    CAS  PubMed  Google Scholar 

  96. Veronikis DK, McClure GB, Nichols DH (1997) The Vecchietti operation for constructing a neovagina: indications, instrumentation, and techniques. Obstet Gynecol 90(2):301–304

    CAS  PubMed  Google Scholar 

  97. Nahas S, Yi J, Magrina J (2013) Mayo clinic experience with modified Vecchietti procedure for vaginal agenesis: it is easy, safe, and effective. J Minim Invasive Gynecol 20(5):553

    PubMed  Google Scholar 

  98. Perez-Medina T, Pereira A, de Argila N, Folgueira G, Iglesias E (2013) Follow-up in women with vaginal agenesis after laparoscopic creation of neovagina. J Minim Invasive Gynecol 20(1):85–89

    PubMed  Google Scholar 

  99. Kdous M, Chaker A, Ferchiou M, Zhioua F (2013) The laparoscopic Vecchietti technique for vaginal agenesis. Tunis Med 91(6):371–375

    PubMed  Google Scholar 

  100. Saraf S, Saraf P (2007) McIndoe vaginoplasty: revisited. Internet J Gynecol Obstet 6(2)

  101. Rotmensch J, Rosenshein N, Dillon M, Murphy A, Woodruff JD (1983) Carcinoma arising in the neovagina: case report and review of the literature. Obstet Gynecol 61(4):534–536

    CAS  PubMed  Google Scholar 

  102. Rummel HH, Kuhn W, Heberling D (1985) [Carcinoma formation in a neovagina following vaginoplasty]. Geburtshilfe Frauenheilkd 45(2):124–125 Article in German

    CAS  PubMed  Google Scholar 

  103. Buscema J, Rosenshein NB, Shah K (1987) Condylomata acuminata arising in a neovagina. Obstet Gynecol 69(3 Pt 2):528–530

    CAS  PubMed  Google Scholar 

  104. Sharma JB, Gupta N, Mittal S (2007) Creation of neovagina using oxidized cellulose (surgicel) as a surgical treatment of vaginal agenesis. Arch Gynecol Obstet 275(4):231–235

    CAS  PubMed  Google Scholar 

  105. Fotopoulou C, Sehouli J, Gehrmann N, Schoenborn I, Lichtenegger W (2010) Functional and anatomic results of amnion vaginoplasty in young women with Mayer-Rokitansky-Kuster-Hauser syndrome. Fertil Steril 94(1):317–323

    PubMed  Google Scholar 

  106. Wartusch B, Heim K, Weiss D, Muller-Holzner E, Holbock E, Pinzger G (1990) [HPV infection and cytology in follow-up of laser therapy of condylomata]. Gynecol Rundsch 30 [Suppl 1]:157–160 Article in German

    Google Scholar 

  107. Imrie JE, Kennedy JH, Holmes JD, McGrouther DA (1986) Intraepithelial neoplasia arising in an artificial vagina. Case report. Br J Obstet Gynaecol 93(8):886–888

    CAS  PubMed  Google Scholar 

  108. Steffanoff DN (1973) Late development of squamous cell carcinoma in a split-skin graft lining a vagina. Case report. Plast Reconstr Surg 51(4):454–456

    CAS  PubMed  Google Scholar 

  109. Ghanbari Z, Dahaghin M, Borna S (2006) Long-term outcomes of vaginal reconstruction with and without amnion grafts. Int J Gynaecol Obstet Off Organ Int Fed Gynaecol Obstet 92(2):163–164

    CAS  Google Scholar 

  110. Jasonni VM, La Marca A, Naldi S, Matonti G, D’Anna R (2007) The management of vaginal agenesis: report of 104 cases. Fertil Steril 88(6):1653–1656

    PubMed  Google Scholar 

  111. Hojsgaard A, Villadsen I (1995) McIndoe procedure for congenital vaginal agenesis: complications and results. Br J Plast Surg 48(2):97–102

    CAS  PubMed  Google Scholar 

  112. Klingele CJ, Gebhart JB, Croak AJ, DiMarco CS, Lesnick TG, Lee RA (2003) McIndoe procedure for vaginal agenesis: long-term outcome and effect on quality of life. Am J Obstet Gynecol 189(6):1569–1572

    PubMed  Google Scholar 

  113. Buss JG, Lee RA (1989) McIndoe procedure for vaginal agenesis: results and complications. Mayo Clin Proc Mayo Clin 64(7):758–761

    CAS  Google Scholar 

  114. Barutcu A, Akguner M (1998) McIndoe vaginoplasty with the inflatable vaginal stent. Ann Plast Surg 41(5):568–569

    CAS  PubMed  Google Scholar 

  115. Ozek C, Gurler T, Alper M, Gundogan H, Bilkay U, Songur E et al (1999) Modified McIndoe procedure for vaginal agenesis. Ann Plast Surg 43(4):393–396

    CAS  PubMed  Google Scholar 

  116. Alessandrescu D, Peltecu GC, Buhimschi CS, Buhimschi IA (1996) Neocolpopoiesis with split-thickness skin graft as a surgical treatment of vaginal agenesis: retrospective review of 201 cases. Am J Obstet Gynecol 175(1):131–138

    CAS  PubMed  Google Scholar 

  117. Siemssen PA, Matzen SH (1997) Neovaginal construction in vaginal aplasia and sex-reassignment surgery. Scand J Plast Reconstr Surg Hand Surg Nord Plast Surg Assoc Nord Club Hand Surg 31(1):47–50

    CAS  Google Scholar 

  118. Seccia A, Salgarello M, Sturla M, Loreti A, Latorre S, Farallo E (2002) Neovaginal reconstruction with the modified McIndoe technique: a review of 32 cases. Ann Plast Surg 49(4):379–384

    PubMed  Google Scholar 

  119. Jackson GW (1959) Primary carcinoma of an artificial vagina. Report of a case. Obstet Gynecol 14:534–536

    CAS  PubMed  Google Scholar 

  120. Baltzer J, Zander J (1989) Primary squamous cell carcinoma of the neovagina. Gynecol Oncol 35(1):99–103

    CAS  PubMed  Google Scholar 

  121. Lowe MP, Ault KA, Sood AK (2001) Recurrent carcinoma in situ of a neovagina. Gynecol Oncol 80(3):403–404

    CAS  PubMed  Google Scholar 

  122. Frost-Arner L, Aberg M, Jacobsson S (2004) Split skin graft reconstruction in vaginal agenesis: a long-term follow-up. Scand J Plast Reconstr Surg Hand Surg Nord Plast Surg Assoc Nord Club Hand Surg 38(3):151–154

    Google Scholar 

  123. Duckler L (1972) Squamous cell carcinoma developing in an artificial vagina. Obstet Gynecol 40(1):35–38

    CAS  PubMed  Google Scholar 

  124. Hopkins MP, Morley GW (1987) Squamous cell carcinoma of the neovagina. Obstet Gynecol 69(3 Pt 2):525–527

    CAS  PubMed  Google Scholar 

  125. Idrees MT, Deligdisch L, Altchek A (2009) Squamous papilloma with hyperpigmentation in the skin graft of the neovagina in Rokitansky syndrome: literature review of benign and malignant lesions of the neovagina. J Pediatr Adolesc Gynecol 22(5):e148–e155

    PubMed  Google Scholar 

  126. Keser A, Bozkurt N, Taner OF, Sensoz O (2005) Treatment of vaginal agenesis with modified Abbe-McIndoe technique: long-term follow-up in 22 patients. Eur J Obstet Gynecol Reprod Biol 121(1):110–116

    PubMed  Google Scholar 

  127. Lin WC, Chang CY, Shen YY, Tsai HD (2003) Use of autologous buccal mucosa for vaginoplasty: a study of eight cases. Hum Reprod 18(3):604–607

    CAS  PubMed  Google Scholar 

  128. Zhao M, Li P, Li S, Li Q (2009) Use of autologous micromucosa graft for vaginoplasty in vaginal agenesis. Ann Plast Surg 63(6):645–649

    CAS  PubMed  Google Scholar 

  129. Tercan M, Balat O, Bekerecioglu M, Atik B (2002) The use of fibrin glue in the McIndoe technique of vaginoplasty. Plast Reconstr Surg 109(2):706–709

    PubMed  Google Scholar 

  130. Sabino Neto M, Baracat EC, Ferreira LM (2001) Vaginal reconstruction by McIndoe technique with a vaginal expander mold. Int J Gynaecol Obstet Off Organ Int Fed Gynaecol Obstet 73(2):165–167

    CAS  Google Scholar 

  131. Schaffer J, Fabricant C, Carr BR (2002) Vaginal vault prolapse after nonsurgical and surgical treatment of Müllerian agenesis. Obstet Gynecol 99(5 Pt 2):947–949

    PubMed  Google Scholar 

  132. Sarwar I, Sultana R, Nisa RU, Qayyum I (2010) Vaginoplasty by using amnion graft in patients of vaginal agenesis associated with Mayor-Rokitansky-Kuster-Hauser syndrome. J Ayub Med Coll Abbottabad 22(1):7–10

    PubMed  Google Scholar 

  133. Motoyama S, Laoag-Fernandez JB, Mochizuki S, Yamabe S, Maruo T (2003) Vaginoplasty with Interceed absorbable adhesion barrier for complete squamous epithelialization in vaginal agenesis. Am J Obstet Gynecol 188(5):1260–1264

    PubMed  Google Scholar 

  134. Dornelas J, Jarmy-Di Bella ZI, Heinke T, Kajikawa MM, Takano CC, Zucchi EV et al (2012) Vaginoplasty with oxidized cellulose: anatomical, functional and histological evaluation. Eur J Obstet Gynecol Reprod Biol 163(2):204–209

    CAS  PubMed  Google Scholar 

  135. Abrenio JK, Chung HI, Pomante R (1977) Verrucous carcinoma arising from an artificial vagina. Obstet Gynecol 50 [1 Suppl]:18s–21s

    CAS  PubMed  Google Scholar 

  136. Zhu L, Zhou H, Sun Z, Lou W, Lang J (2013) Anatomic and sexual outcomes after vaginoplasty using tissue-engineered biomaterial graft in patients with Mayer-Rokitansky-Kuster-Hauser syndrome: a new minimally invasive and effective surgery. J Sex Med 10(6):1652–1658

    PubMed  Google Scholar 

  137. Ghirardini G, Baraldi R, Bertellini C (1998) Severe coital injury after Frank’s creation of a neovagina. Clin Exp Obstet Gynecol 25(4):147–148

    CAS  PubMed  Google Scholar 

  138. Balik E, Maral I, Sozen U, Bezircioglu I, Tugsel Z, Velibese S (1992) [Carcinoma of a Davydov neovagina]. Geburtshilfe Frauenheilkd 52(1):68–69 Article in German

    CAS  PubMed  Google Scholar 

  139. Tamaya T, Fujimoto J (1997) Comparison between transabdominal-vulvar and transvulvar approaches for peritoneal vaginoplasty in patients with congenital absence of the vagina. Eur J Obstet Gynecol Reprod Biol 72(1):79–81

    CAS  PubMed  Google Scholar 

  140. Marques Hde S, dos Santos FL, Lopes-Costa PV, dos Santos AR, da Silva BB (2008) Creation of a neovagina in patients with Rokitansky syndrome using peritoneum from the pouch of Douglas: an analysis of 48 cases. Fertil Steril 90(3):827–832

    PubMed  Google Scholar 

  141. Bianchi S, Frontino G, Ciappina N, Restelli E, Fedele L (2011) Creation of a neovagina in Rokitansky syndrome: comparison between two laparoscopic techniques. Fertil Steril 95(3):1098–1100, e1–3

    PubMed  Google Scholar 

  142. Fedele L, Frontino G, Motta F, Peruzzi E (2011) Davydov’s procedure for the treatment of neovaginal prolapse in Rokitansky syndrome. J Minim Invasive Gynecol 18(4):503–506

    PubMed  Google Scholar 

  143. Adamian LV, Zurabiani Z, Kiselev SI, Khashukoeva AZ (1996) Laparoscopy in surgical treatment of vaginal aplasia: laparoscopy-assisted colpopoiesis and perineal hysterectomy with colpopoiesis. Int J Fertil Menopausal Stud 41(1):40–45

    CAS  PubMed  Google Scholar 

  144. Zhou JH, Sun J, Yang CB, Xie ZW, Shao WQ, Jin HM (2010) Long-term outcomes of transvestibular vaginoplasty with pelvic peritoneum in 182 patients with Rokitansky’s syndrome. Fertil Steril 94(6):2281–2285

    PubMed  Google Scholar 

  145. Gu Y, Zhang X, Kong B, Yu Y (2010) Neovagina constructed with the peritoneum of the anterior abdominal wall. J Obstet Gynaecol Res 36(3):651–655

    PubMed  Google Scholar 

  146. Allen LM, Lucco KL, Brown CM, Spitzer RF, Kives S (2010) Psychosexual and functional outcomes after creation of a neovagina with laparoscopic Davydov in patients with vaginal agenesis. Fertil Steril 94(6):2272–2276

    PubMed  Google Scholar 

  147. Soong YK, Chang FH, Lai YM, Lee CL, Chou HH (1996) Results of modified laparoscopically assisted neovaginoplasty in 18 patients with congenital absence of vagina. Hum Reprod 11(1):200–203

    CAS  PubMed  Google Scholar 

  148. Giannesi A, Marchiole P, Benchaib M, Chevret-Measson M, Mathevet P, Dargent D (2005) Sexuality after laparoscopic Davydov in patients affected by congenital complete vaginal agenesis associated with uterine agenesis or hypoplasia. Hum Reprod 20(10):2954–2957

    CAS  PubMed  Google Scholar 

  149. Liu X, Liu M, Hua K, Li B, Guo SW (2009) Sexuality after laparoscopic peritoneal vaginoplasty in women with Mayer-Rokitansky-Kuster-Hauser syndrome. J Minim Invasive Gynecol 16(6):720–729

    PubMed  Google Scholar 

  150. Ma Y, Qin R, Bi H, Yang X, Zhang J, Yuan J et al (2009) The use of peritoneal tissue mobilised with a novel laparoscopic technique to reconstruct a neovagina. J Plast Reconstr Aesthet Surg 62(3):326–330

    PubMed  Google Scholar 

  151. Creatsas G, Deligeoroglou E, Christopoulos P (2010) Creation of a neovagina after Creatsas modification of Williams vaginoplasty for the treatment of 200 patients with Mayer-Rokitansky-Kuster-Hauser syndrome. Fertil Steril 94(5):1848–1852

    PubMed  Google Scholar 

  152. Steiner E, Woernle F, Kuhn W, Beckmann K, Schmidt M, Pilch H et al (2002) Carcinoma of the neovagina: case report and review of the literature. Gynecol Oncol 84(1):171–175

    PubMed  Google Scholar 

  153. Creatsas G, Deligeoroglou E (2010) Creatsas modification of Williams vaginoplasty for reconstruction of the vaginal aplasia in Mayer-Rokitansky-Kuster-Hauser syndrome cases. Womens Health (Lond Engl) 6(3):367–375

    Google Scholar 

  154. Creatsas G, Christopoulos P (2009) Creatsas modification of Williams vaginoplasty: more than 20 years of experience. Fertil Steril 92(6):e61, author reply e2

    PubMed  Google Scholar 

  155. Walch K, Kowarik E, Leithner K, Schatz T, Dorfler D, Wenzl R (2011) Functional and anatomic results after creation of a neovagina according to Wharton-Sheares-George in patients with Mayer-Rokitansky-Kuster-Hauser syndrome-long-term follow-up. Fertil Steril 96(2):492–497.e1

    PubMed  Google Scholar 

  156. Fliegner JR (1996) Long-term satisfaction with Sheares vaginoplasty for congenital absence of the vagina. Aust N Z J Obstet Gynaecol 36(2):202–204

    CAS  PubMed  Google Scholar 

  157. Kokcu A, Tosun M, Alper T, Sakinci M (2011) Primary carcinoma of the neovagina: a case report. Eur J Gynaecol Oncol 32(5):588–589

    CAS  PubMed  Google Scholar 

  158. Prakash V (2011) Triple flap vaginoplasty for agenesis of the vagina. J Obstet Gynaecol Res 37(6):501–504

    PubMed  Google Scholar 

  159. Creatsas G, Deligeoroglou E (2010) Vaginal aplasia and reconstruction. Best Pract Res Clin Obstet Gynaecol 24:185–191

    CAS  PubMed  Google Scholar 

  160. Marzieh G, Soodabeh D, Narges IM, Saghar SS, Sara E (2011) Vaginal reconstruction using no grafts with evidence of squamous epithelialization in neovaginal vault: a simple approach. J Obstet Gynaecol Res 37(3):195–201

    PubMed  Google Scholar 

  161. Lappohn RE (1995) Congenital absence of the vagina—results of conservative treatment. Eur J Obstet Gynecol Reprod Biol 59(2):183–186

    CAS  PubMed  Google Scholar 

  162. Liao L, Doyle J, Crouch NS, Creighton SM (2006) Dilation as treatment for vaginal agenesis and hypoplasia: a pilot exploration of benefits and barriers as perceived by patients. J Obstet Gynaecol J Inst Obstet Gynaecol 26(2):144–148

    Google Scholar 

  163. Calcagno M, Pastore M, Bellati F, Plotti F, Maffucci D, Boni T et al (2010) Early prolapse of a neovagina created with self-dilatation and treated with sacrospinous ligament suspension in a patient with Mayer-Rokitansky-Kuster-Hauser syndrome: a case report. Fertil Steril 93(1):267.e1–267.e4

    Google Scholar 

  164. Liao LM, Conway GS, Ismail-Pratt I, Bikoo M, Creighton SM (2011) Emotional and sexual wellness and quality of life in women with Rokitansky syndrome. Am J Obstet Gynecol 205(2):117.e1–117.e6

    Google Scholar 

  165. Christopoulos P, Cutner A, Vashisht A, Creighton SM (2011) Laparoscopic sacrocolpopexy to treat prolapse of the neovagina created by vaginal dilation in Rokitansky syndrome. J Pediatr Adolesc Gynecol 24(2):e33–e34

    PubMed  Google Scholar 

  166. Robson S, Oliver GD (2000) Management of vaginal agenesis: review of 10 years practice at a tertiary referral centre. Aust N Z J Obstet Gynaecol 40(4):430–433

    CAS  PubMed  Google Scholar 

  167. Edmonds DK, Rose GL, Lipton MG, Quek J (2012) Mayer-Rokitansky-Kuster-Hauser syndrome: a review of 245 consecutive cases managed by a multidisciplinary approach with vaginal dilators. Fertil Steril 97(3):686–690

    PubMed  Google Scholar 

  168. Ramaswamy S, Kadambari (1986) Mullerian agenesis with vaginal prolapse. Case report. Br J Obstet Gynaecol 93(6):640–641

    CAS  PubMed  Google Scholar 

  169. Burns E, Naim M, Badawy SZ (2012) Mullerian agenesis with vaginal vault prolapse following mechanically created neovagina. J Pediatr Adolesc Gynecol 25(3):e75–e76

    PubMed  Google Scholar 

  170. Mizia K, Bennett MJ, Dudley J, Morrisey J (2006) Mullerian dysgenesis: a review of recent outcomes at Royal Hospital for Women. Aust N Z J Obstet Gynaecol 46(1):29–31

    PubMed  Google Scholar 

  171. Creighton S, Crouch N, Deans R, Cutner A, Michala L, Barnett M et al (2012) Nonsurgical dilation for vaginal agenesis is promising, but better research is needed. Fertil Steril 97(6):e32

    PubMed  Google Scholar 

  172. Ismail-Pratt IS, Bikoo M, Liao LM, Conway GS, Creighton SM (2007) Normalization of the vagina by dilator treatment alone in Complete Androgen Insensitivity Syndrome and Mayer-Rokitansky-Kuster-Hauser Syndrome. Hum Reprod 22(7):2020–2024

    PubMed  Google Scholar 

  173. Bach F, Glanville JM, Balen AH (2011) An observational study of women with mullerian agenesis and their need for vaginal dilator therapy. Fertil Steril 96(2):483–486

    PubMed  Google Scholar 

  174. Tewari DS, McHale MT, Kuo JV, Monk BJ, Burger RA (2002) Primary invasive vaginal cancer in the setting of the Mayer-Rokitansky-Kuster-Hauser syndrome. Gynecol Oncol 85(2):384–387

    PubMed  Google Scholar 

  175. Peters WA 3rd, Uhlir JK (1990) Prolapse of a neovagina created by self-dilatation. Obstet Gynecol 76(5 Pt 2):904–906

    PubMed  Google Scholar 

  176. Minto CL, Liao KL-M, Conway GS, Creighton SM (2003) Sexual function in women with complete androgen insensitivity syndrome. Fertil Steril 80(1):157–164

    PubMed  Google Scholar 

  177. Gargollo PC, Cannon GM Jr, Diamond DA, Thomas P, Burke V, Laufer MR (2009) Should progressive perineal dilation be considered first line therapy for vaginal agenesis? J Urol 182 [4 Suppl]:1882–1889

    PubMed  Google Scholar 

  178. Muir TW, Walters MD (2004) Surgical management of vaginal vault prolapse in a woman with a neovagina and pelvic kidneys. Obstet Gynecol 104(5 Pt 2):1199–1201

    PubMed  Google Scholar 

  179. Bellati F, Calcagno M, Pastore M, Maffucci D, Celentano C, Boni T et al (2009) Vaginal apex necrosis following use of the Frank method of dilation for vaginal agenesis due to Mayer-Rokitansky-Kuster-Hauser syndrome. Int J Gynaecol Obstet Off Organ Int Fed Gynaecol Obstet 107(3):254

    Google Scholar 

  180. Roberts CP, Haber MJ, Rock JA (2001) Vaginal creation for mullerian agenesis. Am J Obstet Gynecol 185(6):1349–1352, discussion 52–53

    CAS  PubMed  Google Scholar 

  181. Kimberley N, Hutson JM, Southwell BR, Grover SR (2011) Well-being and sexual function outcomes in women with vaginal agenesis. Fertil Steril 95(1):238–241

    PubMed  Google Scholar 

  182. Vainright JR Jr, Fulp CJ Jr, Schiebler ML (1988) MR imaging of vaginal agenesis with hematocolpos. J Comput Assist Tomogr 12(5):891–893

    PubMed  Google Scholar 

  183. Frega A, Scirpa P, Sopracordevole F, Biamonti A, Bianchi P, De Sanctis L et al (2011) Impact of human papillomavirus infection on the neovaginal and vulval tissues of women who underwent surgical treatment for Mayer-Rokitansky-Kuster-Hauser syndrome. Fertil Steril 96(4):969–973

    PubMed  Google Scholar 

  184. Sundstrom K, Eloranta S, Sparen P, Arnheim Dahlstrom L, Gunnell A, Lindgren A et al (2010) Prospective study of human papillomavirus (HPV) types, HPV persistence, and risk of squamous cell carcinoma of the cervix. Cancer Epidemiol Biomarkers Prev 19(10):2469–2478

    PubMed Central  PubMed  Google Scholar 

  185. Malka D, Anquetil C, Ruszniewski P (2000) Ulcerative colitis in a sigmoid neovagina. N Engl J Med 343(5):369

    CAS  PubMed  Google Scholar 

  186. Gabarain G, Garcia-Naveiro R, Ponsky TA, Boulanger SC, Parry RL (2012) Ulcerative colitis of the neovagina as a postsurgical complication of persistent cloaca. J Pediatr Surg 47(1):e19–e22

    PubMed  Google Scholar 

  187. Moher D, Liberati A, Tetzlaff J, Altman DG (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med 151(4):264–269, W64

    PubMed  Google Scholar 

  188. Routh JC, Laufer MR, Cannon GM Jr, Diamond DA, Gargollo PC (2010) Management strategies for Mayer-Rokitansky-Kuster-Hauser related vaginal agenesis: a cost-effectiveness analysis. J Urol 184(5):2116–2121

    PubMed  Google Scholar 

  189. Moen MH (2000) Creation of a vagina by repeated coital dilatation in four teenagers with vaginal agenesis. Acta Obstet Gynecol Scand 79(2):149–150

    CAS  PubMed  Google Scholar 

  190. McVearry ME, Warner WB (2011) Use of physical therapy to augment dilator treatment for vaginal agenesis. Female Pelvic Med Reconstr Surg 17(3):153–156

    PubMed  Google Scholar 

  191. Callens N, De Cuypere G, Wolffenbuttel KP, Beerendonk CC, van der Zwan YG, van den Berg M et al (2012) Long-term psychosexual and anatomical outcome after vaginal dilation or vaginoplasty: a comparative study. J Sex Med 9(7):1842–1851

    PubMed  Google Scholar 

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McQuillan, S.K., Grover, S.R. Dilation and surgical management in vaginal agenesis: a systematic review. Int Urogynecol J 25, 299–311 (2014). https://doi.org/10.1007/s00192-013-2221-9

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