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Presence of anterior temporal artery associates with good outcome in acute atherosclerotic M1-middle cerebral artery occlusion

  • Diagnostic Neuroradiology
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Abstract

Introduction

We aim to investigate the correlation between presence of anterior temporal artery (ATA), the first major branch of middle cerebral artery (MCA), on conventional angiography and clinical outcome in patients with acute atherosclerotic M1-MCA occlusion.

Methods

Consecutive patients with acute atherosclerotic M1-MCA occlusion from Nanjing Stroke Registry Program (NSRP) between January 2007 and December 2012 were included in this study. All patients underwent MRI followed by conventional angiography. From their data, we analyzed baseline characteristics, infarction patterns, DWI-ASPECTS, and collateral circulation. The correlation of ATA presence and good clinical outcome, modified Rankin Scale (mRS) score ≤2, at 3 months was also calculated.

Results

In 98 patients meeting entry criteria, the presence of ATA was found in 44 patients. Patients with ATA present were found to have less hypertension (p = 0.042), lower baseline National Institutes of Health Stroke Scale (NIHSS) (p = 0.043), more small infarcts in perforating artery territory (p = 0.013), and a higher number of DWI-ASPECTS ≥7 (p = 0.034). Binary logistic regression analysis showed an adjusted odds ratio of 4.45 for a good outcome in patients with ATA presence (95 % CI 1.52 to 13.03, p = 0.007).

Conclusion

The presence of ATA can be used as a predictor of good outcome in patients with acute atherosclerotic M1-MCA occlusion.

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Ethical standards and patient consent

We declare that this study has been approved by the Institutional Review Board of Jinling Hospital (Nanjing, China) and has therefore been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments. We declare that all patients gave informed consent prior to inclusion in this study.

Acknowledgments

This study was supported by grants from National Natural Science Foundation of China (Grant no. 81000501), Jinling Hospital Medical Scientific Research Projects (2012003), and the Clinical Medical Center Program of Jiangsu Province (Neurology Center). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. We thank Nathan Xuan Cong for help with revising this manuscript.

Conflict of interest

We declare that we have no conflict of interest.

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Correspondence to Xinfeng Liu.

Additional information

Dezhi Liu and Yongkun Li contributed equally to this work.

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Liu, D., Li, Y., Shi, Z. et al. Presence of anterior temporal artery associates with good outcome in acute atherosclerotic M1-middle cerebral artery occlusion. Neuroradiology 56, 1023–1030 (2014). https://doi.org/10.1007/s00234-014-1422-3

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  • DOI: https://doi.org/10.1007/s00234-014-1422-3

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