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Structure, biosynthesis, and properties of kurstakins, nonribosomal lipopeptides from Bacillus spp.

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Abstract

A new family of lipopeptides produced by Bacillus thuringiensis, the kurstakins, was discovered in 2000 and considered as a biomarker of this species. Kurstakins are lipoheptapeptides displaying antifungal activities against Stachybotrys charatum. Recently, the biosynthesis mechanism, the regulation of this biosynthesis and the potential new properties of kurstakins were described in the literature. In addition, kurstakins were also detected in other species belonging to Bacillus genus such as Bacillus cereus. This mini-review gathers all the information about these promising bioactive molecules.

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Acknowledgments

This work received financial support from the Université Lille 1, Sciences et Technologies and ARCIR funds from Nord-Pas-de-Calais and the European Funds of INTERREG IV PhytoBio Project. We acknowledge William Everett for his kind English proofreading.

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Correspondence to Philippe Jacques.

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Béchet, M., Caradec, T., Hussein, W. et al. Structure, biosynthesis, and properties of kurstakins, nonribosomal lipopeptides from Bacillus spp.. Appl Microbiol Biotechnol 95, 593–600 (2012). https://doi.org/10.1007/s00253-012-4181-2

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  • DOI: https://doi.org/10.1007/s00253-012-4181-2

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