Abbreviations
- ADCC:
-
Antibody-dependent cell-mediated cytotoxicity
- BCMA:
-
Bispecific B-cell maturation antigen
- CDK:
-
Cyclin-dependent kinase
- cHL:
-
Classical Hodgkin’s lymphoma
- CLDN:
-
Claudin
- MEK:
-
Mitogen-activated kinase kinase
- MSI-H:
-
Microsatellite instability high
- Smac:
-
Second mitochondria-derived activator of caspase
- STING:
-
Stimulator of interferon genes protein
- TIGIT:
-
T cell immunoreceptor with Ig and ITIM domains
- TRAF:
-
TNF receptor associated factor
- Trex:
-
Three prime repair exonuclease
- T-vec:
-
Talimogene laherparepvec
Acknowledgements
We are grateful to Belen Palencia, Esther Guirado and Cibeles Pinto for excellent meeting logistics.
Funding
The meeting was supported by the Ramón Areces foundation, Center for Applied Medical Research (CIMA), Clínica Universidad de Navarra, GETICA, GEIT, REINCA, IDISNA, ADITECH and the following pharmaceutical companies: AstraZeneca, Takeda, Lilly, Merck, Merck Sharp & Dohme Corp (MSD), Roche, Bristol-Myers Squibb and Boehringer-Ingelheim.
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All authors made notes at the symposium which served as the basis for this meeting report. PB and IM wrote the manuscript, and all authors completed and approved the final version.
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Conflict of interest
Ignacio Melero is a consultant for Bristol-Myers Squibb, Roche-Genentech, Medimmune, Merck Serono, Bioncotech, F-STAR, Genemab and Tusk. He receives grants from Bristol-Myers Squibb, Roche-Genentech and Alligator. Jose Luis Perez-Gracia is an advisor to Bristol Myers and Roche-Genentech. The rest of the authors declare that they have no conflicts of interest.
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Berraondo, P., Aznar, M.A., Perez-Ruiz, E. et al. International Symposium: Trailblazing in Cancer Immunotherapy, October 29–31, 2017, Pamplona, Spain. Cancer Immunol Immunother 67, 1809–1813 (2018). https://doi.org/10.1007/s00262-018-2240-y
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DOI: https://doi.org/10.1007/s00262-018-2240-y