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Medikamentöse Therapie des Nystagmus

Pharmacological treatment of nystagmus

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Zusammenfassung

Ein Nystagmus kann mit erheblichen Beschwerden wie Bildwackeln, Verschwommensehen und Schwindel einhergehen. Da eine kurative Behandlung in der Regel nicht möglich ist, liegt vermehrtes Augenmerk auf den Möglichkeiten einer medikamentösen Nystagmusberuhigung. Es erfolgt eine Aufstellung, bei welchen Nystagmusformen welche Medikamente eingesetzt werden können und wie diese im Einzelnen wirken. Ein in kontrollierten Studien nachgewiesener Effekt besteht für Gabapentin und Memantin beim Fixationspendelnystagmus und frühkindlich idiopathischen Nystagmus und von 4-Aminopyridin beim Downbeat-Nystagmus.

Abstract

Nystagmus can be associated with strong discomfort due to oscillopsia, blurry vision and dizziness. Since generally no curative treatment methods exist, studies focus on potential pharmaceuticals to dampen the nystagmus. An overview is given on which forms of nystagmus can be treated with what kind of pharmacological substances and their possible mechanism of nystagmus dampening. Controlled studies found gabapentin and memantine to be effective in acquired pendular nystagmus and early-onset idiopathic nystagmus, and an efficacy of 4-aminopyridine in downbeat nystagmus.

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  1. Universitäts-Augenklinik Freiburg, Killianstr. 5, 79106, Freiburg, Deutschland

    C. Pieh-Beisse & W.A. Lagrèze

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  1. C. Pieh-Beisse
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  2. W.A. Lagrèze
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Correspondence to C. Pieh-Beisse.

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Pieh-Beisse, C., Lagrèze, W. Medikamentöse Therapie des Nystagmus. Ophthalmologe 108, 178–182 (2011). https://doi.org/10.1007/s00347-010-2324-3

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  • DOI: https://doi.org/10.1007/s00347-010-2324-3

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