References
Kinis V, Ozbay M, Alabalik U, Gul A, Yilmaz B, Ozkurt FE, Songul E, Topcu I (2015) Effect of caffeic acid phenethyl ester on myringosclerosis development in the tympanic membrane of rat. Eur Arch Otorhinolaryngol 272:29–34
Akyol S, Ginis Z, Armutcu F, Ozturk G, Yigitoglu MR, Akyol O (2012) The potential usage of caffeic acid phenethyl ester (CAPE) against chemotherapy-induced and radiotherapy-induced toxicity. Cell Biochem Funct 30:438–443
Wang X, Pang J, Maffucci JA et al (2009) Pharmacokinetics of caffeic acid phenethyl ester and its catechol-ring fluorinated derivative following intravenous administration to rats. Biopharm Drug Dispos 30:221–228
Celli N, Dragani LK, Murzilli S et al (2007) In vitro and in vivo stability of caffeic acid phenethyl ester, a bioactive compound of propolis. J Agric Food Chem 55:3398–3407
Burdock GA (1998) Review of the biological properties and toxicity of bee propolis (propolis). Food Chem Toxicol 36:347–363
Akyol S, Isik B, Altuntas A, Erden G, Cakmak O, Kursunlu SF, Adam B, Akyol O (2015) Future opportunities in preventing ototoxicity: Can caffeic acid phenethyl ester (CAPE) be a candidate? Mol Med Rep. doi:10.3892/mmr.2015.3785
Kizilay A, Kalcioglu MT, Ozerol E, Iraz M, Gulec M, Akyol O, Ozturan O (2004) Caffeic acid phenethyl ester ameliorated ototoxicity induced by cisplatin in rats. J Chemother 16:381–387
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Erdemli, H.K., Akyol, S., Armutcu, F. et al. The possible preventive effect of caffeic acid phenethyl ester (CAPE) against myringosclerosis. Eur Arch Otorhinolaryngol 273, 789–790 (2016). https://doi.org/10.1007/s00405-015-3690-x
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DOI: https://doi.org/10.1007/s00405-015-3690-x