References
Jefford M, Mileshkin L, Matthews J, Raunow H, O’Kane C, Cavicchiolo T et al (2011) Satisfaction with the decision to participate in cancer clinical trials is high, but understanding is a problem. Support Care Cancer 19(3):371–379
Joffe S, Cook EF, Cleary PD, Clark JW, Weeks JC (2001) Quality of informed consent: a new measure of understanding among research subjects. J Natl Cancer Inst 93(2):139–147
Joffe S, Cook EF, Cleary PD, Clark JW, Weeks JC (2001) Quality of informed consent in cancer clinical trials: a cross-sectional survey. Lancet 358(9295):1772–1777
Beardsley E, Jefford M, Mileshkin L (2007) Longer consent forms for clinical trials compromise patient understanding: so why are they lengthening? J Clin Oncol 25(9):e13–e14
Grossman SA, Piantadosi S, Covahey C (1994) Are informed consent forms that describe clinical oncology research protocols readable by most patients and their families? J Clin Oncol 12(10):2211–2215
Craft PS, Burns CM, Smith WT, Broom DH (2005) Knowledge of treatment intent among patients with advanced cancer: a longitudinal study. Eur J Cancer Care (Engl) 14(5):417–425
Eidinger RN, Schapira DV (1984) Cancer patients’ insight into their treatment, prognosis, and unconventional therapies. Cancer 53(12):2736–2740
Gattellari M, Butow PN, Tattersall MH, Dunn SM, MacLeod CA (1999) Misunderstanding in cancer patients: why shoot the messenger? Ann Oncol 10(1):39–46
Mackillop WJ, Stewart WE, Ginsburg AD, Stewart SS (1988) Cancer patients’ perceptions of their disease and its treatment. Br J Cancer 58(3):355–358
Pronzato P, Bertelli G, Losardo P, Landucci M (1994) What do advanced cancer patients know of their disease? A report from Italy. Support Care Cancer 2(4):242–244
Jefford M, Moore R (2008) Improvement of informed consent and the quality of consent documents. Lancet Oncol 9(5):485–493
Tattersall MH, Gattellari M, Voigt K, Butow PN (2002) When the treatment goal is not cure: are patients informed adequately? Support Care Cancer 10(4):314–321
Jansen LA, Appelbaum PS, Klein WM, Weinstein ND, Cook W, Fogel JS et al (2011) Unrealistic optimism in early-phase oncology trials. IRB 33(1):1–8
Weeks JC, Cook EF, O’Day SJ, Peterson LM, Wenger N, Reding D et al (1998) Relationship between cancer patients' predictions of prognosis and their treatment preferences. JAMA 279(21):1709–1714
Acknowledgments
No sources of funding were used to assist in the preparation of this manuscript. The authors have no conflicts of interest that are directly relevant to the contents of this review. No other persons have made substantial contributions to this work.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Yoong, J., Jefford, M. & Mileshkin, L. Patients’ understanding of clinical trials needs to be assessed in the context of understanding of overall goals of care. Support Care Cancer 19, 1067–1068 (2011). https://doi.org/10.1007/s00520-011-1201-1
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00520-011-1201-1