Abstract
Objectives
This paper aims to examine the cross-sectional and longitudinal associations between patient-reported unmet needs and anxiety and depression for survivors of diffuse large B cell lymphoma (DLBCL) and multiple myeloma (MM).
Methods
In a longitudinal study design, self-reported data were collected through telephone interviews at two time points approximately 7 (T1) and 15 (T2) months post-diagnosis. The sample was recruited through the population-based Victorian Cancer Registry. At T1 and T2, the study outcomes, anxiety and depression, were assessed using the Hospital Anxiety and Depression Scale (HADS) and unmet needs were measured using the Supportive Care Needs Survey (SCNS-SF34). Questions related to social/family problems, relationship problems and financial problems were also asked. A three-step multivariable hierarchical logistic regression analysis examined the relative role of T1 anxiety and depression, T1 and T2 unmet needs and other psychosocial factors with T2 anxiety and depression.
Results
Both cross-sectional and longitudinal associations were observed between unmet needs and psychological distress. T2 anxiety was associated with T1 anxiety (OR 4.75, 95% CI 1.86–11.09), T2 psychological needs (OR 1.68, 95% CI 1.34–2.11) and with T1 social problems (OR 2.33, 95% CI 1.03–5.05) in multivariate analysis. T2 depression was associated with both T1 (OR 1.28, 95% CI 1.06–1.57) and T2 psychological needs (OR 1.35, 95% CI 1.06–1.70), T2 physical needs (OR 1.89, 95% CI 1.27–2.81) and T1 depression (OR 4.52, 95% CI 1.88–10.86).
Conclusions
Unmet needs that manifest following diagnosis and treatment may persist into early survivorship and contribute to psychological distress. Addressing these needs during treatment may diminish the risk of current and future anxiety and depression.
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References
Smith A, Howell D, Patmore R et al (2011) Incidence of haematological malignancy by sub-type: a report from the Haematological Malignancy Research Network. Br J Cancer 105(11):1684–1692
Wang Z-Y, Liu L, Shi M et al (2015) Exploring correlations between positive psychological resources and symptoms of psychological distress among hematological cancer patients: a cross-sectional study. Psychology, Health & Medicine 21(5):571–582
Bergerot CD, Clark KL, Nonino A et al (2015) Course of distress, anxiety, and depression in hematological cancer patients: association between gender and grade of neoplasm. Palliat Support Care 13(02):115–123
Priscilla D, Hamidin A, Azhar MZ et al (2011) Assessment of depression and anxiety in haematological cancer patients and their relationship with quality of life. East Asian Arch Psychiatry 21(3):108–114
Clinton-McHarg T, Carey M, Sanson-Fisher R et al (2014) Anxiety and depression among haematological cancer patients attending treatment centres: prevalence and predictors. J Affect Disord 165:176–181
Hall AE, Sanson-Fisher RW, Carey ML, et al. (2016) Prevalence and associates of psychological distress in haematological cancer survivors. Support Care Cancer 24:4413–4422
Albrecht TA, Rosenzweig M (2012) Management of cancer related distress in patients with a hematological malignancy. Journal of Hospice and Palliative Nursing: JHPN: the Official Journal of the Hospice and Palliative Nurses Association 14(7):462
Sanson-Fisher R, Girgis A, Boyes A et al (2000) The unmet supportive care needs of patients with cancer. Supportive care review group. Cancer 88(1):226–237
Hall A, Lynagh M, Bryant J, et al. (2013) Supportive care needs of hematological cancer survivors: a critical review of the literature. Crit Rev Oncol/Hematol 88:102–116
Fitch MI (2008) Supportive care framework. Can Oncol Nurs J 18(1):6–24
Sanson-Fisher R, Carey M, Paul C (2009) Measuring the unmet needs of those with cancer: a critical overview. Cancer Forum 33(3). http://cancerforum.org.au/wp-content/uploads/2015/06/CF09Nov_198-201.pdf
Cohen S (2004) Social relationships and health. Am Psychol 59(8):676
Maly RC, Umezawa Y, Leake B et al (2005) Mental health outcomes in older women with breast cancer: impact of perceived family support and adjustment. Psychooncology 14(7):535–545
Uchida M, Akechi T, Okuyama T et al (2011) Patients’ supportive care needs and psychological distress in advanced breast cancer patients in Japan. Jpn J Clin Oncol 41(4):530–536
Santos FR, Kozasa EH, Maria de Lourdes L et al (2006) Psychosocial adaptation and quality of life among Brazilian patients with different hematological malignancies. J Psychosom res 60(5):505–511
Molassiotis A, Wilson B, Blair S, et al. (2011) Unmet supportive care needs, psychological well-being and quality of life in patients living with multiple myeloma and their partners. Psycho-Oncol 20:88–97
Armes J, Crowe M, Colbourne L et al (2009) Patients’ supportive care needs beyond the end of cancer treatment: a prospective, longitudinal Survey. J Clin Oncol 27(36):6172–6179
Beesley VL, Smithers BM, O’Rourke P et al (2016) Variations in supportive care needs of patients after diagnosis of localised cutaneous melanoma: a 2-year follow-up study. Support Care Cancer 25(1):1–10
Rowlands IJ, Janda M, McKinnon L et al (2015) Prevalence, predictors, and correlates of supportive care needs among women 3–5 years after a diagnosis of endometrial cancer. Support Care Cancer 23(5):1205–1214
Lam WW, Law WL, Poon JT et al (2015) A longitudinal study of supportive care needs among Chinese patients awaiting colorectal cancer surgery. Psycho-Oncology 25(5):496–505
McLachlan S-A, Allenby A, Matthews J et al (2001) Randomized trial of coordinated psychosocial interventions based on patient self-assessments versus standard care to improve the psychosocial functioning of patients with cancer. J Clin Oncol 19(21):4117–4125
Milpied N, Deconinck E, Gaillard F et al (2004) Initial treatment of aggressive lymphoma with high-dose chemotherapy and autologous stem-cell support. N Engl J med 350(13):1287–1295
Thursfield V, Farrugia H. Cancer in Victoria: statistics and trends 2010. Melbourne: Cancer Council Victoria;2011. Available from: www.cancervic.org.au/about-our-research/registry-statistics
Thursfield V, Farrugia H. Cancer in Victoria: statistics & trends 2014. Melbourne, Australia: Cancer Council Victoria;2015. Available from: www.cancervic.org.au/about-our-research/registry-statistics
Zigmond AS, Snaith RP (1983) The Hospital Anxiety and Depression Scale. Acta Psychiatr Scand 67(6):361–370
Bjelland I, Dahl AA, Haug TT et al (2002) The validity of the Hospital Anxiety and Depression Scale: an updated literature review. J Psychosom res 52(2):69–77
Gough K, Hudson P (2009) Psychometric properties of the Hospital Anxiety and Depression Scale in family caregivers of palliative care patients. J Pain Symptom Manag 37(5):797–806
Boyes A, Girgis A, Lecathelinais C (2009) Brief assessment of adult cancer patients’ perceived needs: development and validation of the 34-item Supportive Care Needs Survey (SCNS-SF34). J Eval Clin Pract 15(4):602–606
Green SB (1991) How many subjects does it take to do a regression analysis. Multivar Behav res 26(3):499–510
Hosmer DW, Lemeshow S (2000) Applied logistic regression, 2nd edn. Wiley, New York
Bursac Z, Gauss CH, Williams DK et al (2008) Purposeful selection of variables in logistic regression. Source Code Biol Med 3(1):17
Oerlemans S, Mols F, Nijziel MR et al (2014) The course of anxiety and depression for patients with Hodgkin’s lymphoma or diffuse large B cell lymphoma: a longitudinal study of the profiles registry. J Cancer Surviv 8(4):555–564
Azar RM, Nikoogoftar M, Salehi S et al (2010) Anxiety and depression in pre-and-post-hematopoietic stem cell transplants in Sct Center, Shariati Hospital, Tehran, Iran. Int J Hematol-Oncol Stem Cell Res 4(4):17–21
Hipkins J, Whitworth M, Tarrier N et al (2004) Social support, anxiety and depression after chemotherapy for ovarian cancer: a prospective study. Br J Health Psychol 9(Pt 4):569–581
Traeger L, Greer JA, Fernandez-Robles C et al (2012) Evidence-based treatment of anxiety in patients with cancer. J Clin Oncol 30(11):1197–1205
Thong MSY, Mols F, Stein KD et al (2013) Population-based cancer registries for quality-of-life research. Cancer 119:2109–2123
Campbell HS, Sanson-Fisher R, Turner D et al (2010) Psychometric properties of cancer survivors’ unmet needs survey. Support Care Cancer 19(2):221–230
Boyes AW, Girgis A, D'Este C et al (2012) Prevalence and correlates of cancer survivors’ supportive care needs 6 months after diagnosis: a population-based cross-sectional study. BMC Cancer 12:150
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This project was funded by Victorian Cancer Agency (VCA) Translational Research Grant EOI09_36.
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The authors declare that they have no conflict of interest.
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Oberoi, D., White, V.M., Seymour, J.F. et al. The influence of unmet supportive care needs on anxiety and depression during cancer treatment and beyond: a longitudinal study of survivors of haematological cancers. Support Care Cancer 25, 3447–3456 (2017). https://doi.org/10.1007/s00520-017-3766-9
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DOI: https://doi.org/10.1007/s00520-017-3766-9