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A Green Synthesis of Tetrahydrobenzo[b]pyran Derivatives through Three-Component Condensation Using N-Methylimidazole as Organocatalyst

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Summary.

An efficient and convenient approach to the synthesis of 2-amino-3-cyano-4-aryl-7,7-dimethyl-5-oxo-4H-5,6,7,8-tetrahydrobenzo[b]pyran derivatives using N-methylimidazole as the organocatalyst (20 mol%) is described. This method has several advantages, such as mild conditions, high yields, and simple work-up procedure.

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Authors and Affiliations

  1. Department of Chemistry, Jinan University, Guangzhou, China

    Xi-Zhong Lian, Yu Huang, Yi-Qun Li & Wen-Jie Zheng

Authors
  1. Xi-Zhong Lian
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  2. Yu Huang
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  3. Yi-Qun Li
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  4. Wen-Jie Zheng
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Correspondence to Yi-Qun Li.

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Lian, XZ., Huang, Y., Li, YQ. et al. A Green Synthesis of Tetrahydrobenzo[b]pyran Derivatives through Three-Component Condensation Using N-Methylimidazole as Organocatalyst. Monatsh Chem 139, 129–131 (2008). https://doi.org/10.1007/s00706-007-0706-2

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  • DOI: https://doi.org/10.1007/s00706-007-0706-2

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