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Ferric perchlorate as an efficient and useful catalyst for the selective benzylation and methylation of alcohols with benzyl chloride and methyl iodide

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Abstract

A mild and efficient method was developed for selective benzylation and methylation of hydroxyl compounds in the presence of a catalytic amount of ferric perchlorate. We showed that ferric perchlorate was very effective in selectively promoting the benzylation and methylation of primary aliphatic and benzylic alcohols versus secondary aliphatic alcohols and phenolic hydroxy groups.

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Authors and Affiliations

  1. Department of Chemistry, School of Sciences, Azzahra University, Vanak, Tehran, Iran

    Majid M. Heravi & Hossien A. Oskooie

  2. Department of Chemistry, School of Sciences, Islamic Azad University, Karaj branch, Karaj, Iran

    Farahnaz K. Behbahani

Authors
  1. Farahnaz K. Behbahani
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  2. Majid M. Heravi
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  3. Hossien A. Oskooie
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Correspondence to Majid M. Heravi.

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Behbahani, F.K., Heravi, M.M. & Oskooie, H.A. Ferric perchlorate as an efficient and useful catalyst for the selective benzylation and methylation of alcohols with benzyl chloride and methyl iodide. Monatsh Chem 140, 181–184 (2009). https://doi.org/10.1007/s00706-008-0054-x

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  • DOI: https://doi.org/10.1007/s00706-008-0054-x

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