Summary.
In the present work various free amino acids, including tryptophan and tyrosine, were effectively N-phthaloylated under reduced pressure and at lower temperature. Moreover, under these conditions, the presence of phthalic acid in phthalic anhydride did not hinder the N-phthaloylation of amino acids. This simple process is economic, environmentally friendly, and suitable for large-scale production.
Similar content being viewed by others
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Zeng, Q., Liu, Z., Li, B. et al. Mild and effective N-phthaloylation of amino acids. Amino Acids 27, 183–186 (2004). https://doi.org/10.1007/s00726-004-0109-1
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00726-004-0109-1