Abstract
Clinicians frequently request serologic tests to provide evidence of prior infection by Streptococcus pyogenes, especially when suspecting a diagnosis of acute rheumatic fever or post-streptococcal glomerulonephritis. However, the interpretation of these tests is difficult and should take account of the clinical features, epidemiological setting, and pre-test probability, as well as the specific aspects of the assay. This review details the characteristics of streptococcal serologic assays and provides recommendations for their use and interpretation.
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Parks, T., Smeesters, P.R., Curtis, N. et al. ASO titer or not? When to use streptococcal serology: a guide for clinicians. Eur J Clin Microbiol Infect Dis 34, 845–849 (2015). https://doi.org/10.1007/s10096-014-2303-8
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DOI: https://doi.org/10.1007/s10096-014-2303-8