References
Dai W, Sun S, Yang P, Huang S, Zhang X, Zhang L (2013) Characterization of carbapenemases, extended spectrum β-lactamases and molecular epidemiology of carbapenem-non-susceptible Enterobacter cloacae in a Chinese hospital in Chongqing. Infect Genet 14:1–7
Mezzatesta ML, Gona F, Stefani S (2012) Enterobacter cloacae complex: clinical impact and emerging antibiotic resistance. Future Microbiol 7:887–902
Tato M, Morosini M, Garcia L, Alberti S, Coque MT, Cantón R (2010) Carbapenem heteroresistance in VIM-1-producing Klebsiella pneumoniae isolates belonging to the same clone: consequences for routine susceptibility testing. J Clin Microbiol 48:4089–4093
Zavascki AP, Falci DR, da Silva RC, Dalarosa MG, Ribeiro VB, Rozales FP et al (2014) Heteroresistance to carbapenems in New Delhi Metallo-beta-lactamase-1-producing isolates: a challenge for detection? Infect Control Hosp Epidemiol 35:751–752
El-Halfawy O, Valvano MA (2015) Antimicrobial heteroresistance: an emerging field in need of clarity. Clin Microbiol Rev 28:191–207
Financial support
This work was supported by the “Fundo de Incentivo à Pesquisa e Eventos do Hospital de Clínicas de Porto Alegre” (FIPE/HCPA). A.L.B. and A.F.M are research fellows from the National Council for Scientific and Technological Development, Ministry of Science and Technology, Brazil and received master scholarships from “Coordenação de Aperfeiçoamento de Pessoal de Ensino Superior” (CAPES), Brazil.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors declare they have no conflicts of interest.
Ethical approval
This study was approval by the GPPG/HCPA ethics committee (14-0034).
Rights and permissions
About this article
Cite this article
da Silva, A.E.B., Martins, A.F., Nodari, C.S. et al. Carbapenem-heteroresistance among isolates of the Enterobacter cloacae complex: is it a real concern?. Eur J Clin Microbiol Infect Dis 37, 185–186 (2018). https://doi.org/10.1007/s10096-017-3138-x
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10096-017-3138-x