Skip to main content
SpringerLink
Log in

Comparison of Headspace-Single Drop Microextraction and Dispersive Liquid–Liquid Microextraction for Determination of Benzene in Juice Drinks Containing Vitamin C

  • Short Communication
  • Published:
Chromatographia Aims and scope Submit manuscript

Abstract

In this paper, a fast and effective headspace-single drop microextraction (HS-SDME) method was applied for the determination of traces of benzene in juice drinks containing vitamin C. Benzene is produced in drinks as a result of interaction of sodium benzoate (as food preservative) and ascorbic acid (vitamin C). A mixture of n-hexadecane and n-dodecane was used as extractant in the form of organic drop. Other parameters affecting the extraction of benzene, including volume of organic drop, time of extraction, volume, pH and ionic strength of sample solution, were studied and optimized. The obtained dynamic range under optimised conditions was from 2 to 350 μg L−1 with the limit of detection of 1.49 μg L−1. The obtained data for HS-SDME of benzene were compared with the data obtained for the determination of benzene with dispersive liquid–liquid microextraction (DLLME). It was observed that though DLLME is simpler and faster, the limit of detection and the repeatability of HS-SDME were better.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. Duarte-Davidson R, Courage C, Rushton L, Levy L (2001) Occup Environ Med 58:2–13

    Article  CAS  Google Scholar 

  2. Davidson PM, Sofos JN, Branen AL (eds) (2005) Antimicrobials in food. CRC Press, Boca Raton

    Google Scholar 

  3. Vinci RM, Jacxsens L, Van Loco J, Matsiko E, Lachat C, de Schaetzen T, Canfyn M, Van Overmeire I, Kolsteren P, De Meulenaer B (2012) Chemosphere 88:1001–1007

    Article  Google Scholar 

  4. Styarini D, Zuas O, Hamim N (2011) Eurasian J Anal Chem 6:159–172

    CAS  Google Scholar 

  5. Liu S, Dasgupta PK (1995) Anal Chem 67:2042–2049

    Article  CAS  Google Scholar 

  6. Psillakis E, Kalogerakis N (2003) TRAC Trends in Anal Chem 22:565–574

    Article  CAS  Google Scholar 

  7. Kaykhaii M, Rahmani M (2007) J Sep Sci 30:573–578

    Article  CAS  Google Scholar 

  8. Rahmani M, Kaykhaii M (2011) Microchim Acta 174:413–419

    Article  CAS  Google Scholar 

  9. Kaykhaii M, Noorinejad S (2014) J Anal Atom Spectrom 29:875–879

    Article  CAS  Google Scholar 

  10. Rezaee M, Assadi Y, Milani Hosseini MR, Aghaee E, Ahmadi F, Berijani S (2006) J Chromatogr A 1116:1–9

    Article  CAS  Google Scholar 

  11. Assadi Y, Ahmadi F, Milani Hossieni MR (2010) Chromatographia 71:1137–1141

    Article  CAS  Google Scholar 

  12. Stadler RH, Lineback DR (2009) Process-induced food toxicants: occurrence, formation, mitigation, and health risks. Wiley, New York

    Google Scholar 

  13. Aksoy A, Sahin U, Duman F (2000) Turk J Bot 24:279–284

    Google Scholar 

  14. Bowles KC, Apte SC, Batley GE, Hales LT, Rogers NJ (2006) Anal Chim Acta 558:237–245

    Article  CAS  Google Scholar 

  15. Sarafraz-Yazdi A, Amiri AH, Es’Haghi Z (2009) Talanta 78:936–941

    Article  CAS  Google Scholar 

  16. Khajeh M, Zadeh FM (2012) B Environ Contam Tox 89:38–43

    Article  CAS  Google Scholar 

  17. Es’haghi Z, Ebrahimi M, Hosseini (2011) J Chromatogr A 1218:3400–3406

    Article  Google Scholar 

  18. Menéndez JF, Sánchez MF, Urıa JS, Martı́nez EF, Sanz-Medel A (2000) Anal Chim Acta 415:9–20

    Article  Google Scholar 

Download references

Acknowledgments

This research was supported by the University of Sistan and Baluchestan.

Author information

Authors and Affiliations

  1. Department of Chemistry, Faculty of Sciences, University of Sistan and Baluchestan, Zahedan, 98135-674, Iran

    Massoud Kaykhaii, Zahra Hosseinbor & Elham Ghasemi

Authors
  1. Massoud Kaykhaii
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Zahra Hosseinbor
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Elham Ghasemi
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Massoud Kaykhaii.

Ethics declarations

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kaykhaii, M., Hosseinbor, Z. & Ghasemi, E. Comparison of Headspace-Single Drop Microextraction and Dispersive Liquid–Liquid Microextraction for Determination of Benzene in Juice Drinks Containing Vitamin C. Chromatographia 79, 781–785 (2016). https://doi.org/10.1007/s10337-016-3096-y

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10337-016-3096-y

Keywords

Search

Navigation