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A novel biotransformation of 2-formyl-6-naphthoic acid to 2,6-naphthalene dicarboxylic acid by Pseudomonas sp. for the purification of crude 2,6-naphthalene dicarboxylic acid

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Abstract

Crude 2,6-naphthalene dicarboxylic acid was purified by Pseudomonas sp. HN-72 which biotransformed the major impurity of 2-formyl-6-naphthoic acid into 2,6-naphthalene dicarboxylic acid. The biotransformation yield reached 100% when the reaction was performed at 40°C for 1 h, in 200 ml KH2PO4/KOH buffer (50 mM, pH 8.0), with 0.2% (w/v) crude 2,6-naphthalene dicarboxylic acid and 2.5 mg dry cell wt/ml.

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Acknowledgement

The researchers wish to thank the Analytical Research Center (Hyosung Corporation) for the technical support it provided in the analysis of crude 2,6-NDA in this study.

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Correspondence to Dong-Sung Kim.

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Kim, DS., Kim, SK., Choi, YB. et al. A novel biotransformation of 2-formyl-6-naphthoic acid to 2,6-naphthalene dicarboxylic acid by Pseudomonas sp. for the purification of crude 2,6-naphthalene dicarboxylic acid. Biotechnol Lett 30, 329–333 (2008). https://doi.org/10.1007/s10529-007-9545-9

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  • DOI: https://doi.org/10.1007/s10529-007-9545-9

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