A new triterpene ester 1 and six known triterpenoids were isolated from Anemone rivularis by repeated column chromatography. Their structures were identified as olean-9(11),12-dien-3-O-palmitate (1), lupeol (2), betulin (3), betulic acid (4), oleanolic acid (5), ursolic acid (6), and β-amyrin (7) by spectral analysis and comparison with the published data. In addition, compound 1 was evaluated in vitro for its antimicrobial activity. It was found to exhibit moderate activity against the Gram-positive bacteria B. subtilis and S. aureus.
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Acknowledgment
This work was partially supported by the programs from the Analytical Detection Center, Shenyang Pharmaceutical University, and the Analytical Detection Center, Shanghai Second Military Medical University, the Analytical Detective Center, Yangzhou University. We are also grateful to Associate Professor Qingde Long, GuiYang Medical College, for identification of the plant.
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Published in Khimiya Prirodnykh Soedinenii, No. 5, September–October, 2012, pp. 717–718.
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Zhao, CC., Shao, JH. & Fan, JD. A new triterpenoid with antimicrobial activity from Anemone rivularis . Chem Nat Compd 48, 803–805 (2012). https://doi.org/10.1007/s10600-012-0387-x
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DOI: https://doi.org/10.1007/s10600-012-0387-x