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Chemiluminescence Determination of Sodium New Houttuyfonate in Pharmaceutical Preparations Based on Tween 80—Rhodamine B System

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Abstract

Strong chemiluminescence (CL) emission was observed when sodium new houttuyfonate (SNH) was mixed with Tween 80 in sulfuric acid medium in the presence of rhodamine B. Base on this phenomenon, a sensitive flow injection-CL method for the determination of SNH was developed. Under the optimum conditions, the CL emission is linearly with SNH concentration in the range 8.0–4000 ng mL−1, with a detection limit of 2.7 ng mL−1 (3σ). As a preliminary application, the proposed method was successfully applied to the determination of SNH in pharmaceutical preparations. The possible CL mechanism was also discussed in this paper.

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Acknowledgements

This work was supported by the Natural Science Foundation of Northwest University of China (04NW46). And the author thanks the Northwest University of China for startup funds.

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Correspondence to Xiao-Feng Yang.

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Yang, XF., Yao, H., Zhai, JB. et al. Chemiluminescence Determination of Sodium New Houttuyfonate in Pharmaceutical Preparations Based on Tween 80—Rhodamine B System. J Fluoresc 17, 15–21 (2007). https://doi.org/10.1007/s10895-006-0150-4

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  • DOI: https://doi.org/10.1007/s10895-006-0150-4

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