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Tryptophan / Dextran70 Based - Fluorescent Silver Nanoparticles: Synthesis and Physicochemical Properties

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Abstract

Nano-size and shape of fluorescent silver nanostructures are important for a wide range of bio-applications, especially as drug delivery systems, imaging and sensing. The aim of the work is to develop a fluorescent silver nano-structured system, synthesized by chemical reduction of aqueous AgNO3 solution by Tryptophan using Dextran 70 as stabilizing agent (SNPsFL). The formed fluorescent nano-system was analyzed by UV-Vis absorption, DLS, SEM, TEM, AFM, steady-state and time resolved fluorescence spectroscopy. TEM analysis showed multi-twined nanoparticle, with the size within 15–40 nm. SNPsFL shows the fluorescence emission at 346 nm, the fluorescence quantum yield, Φ = 0.034 and the integrated fluorescence lifetime, <τ > = 1.82 ns. Riboflavin fluorescence behaviour in the RF/SNPsFL system, has been also studied. The results have relevance in using SNPsFL as a potential marker/emissive system to solve various biological barriers in humans, like drug release and protein structure.

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Acknowledgements

This work was done within the research programme “Quantum Chemistry and Molecular Structure” of the Institute of Physical Chemistry “Ilie Murgulescu” of the Romanian Academy.

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Authors and Affiliations

  1. Institute of Physical Chemistry “Ilie Murgulescu” of the Romanian Academy, Splaiul Independentei 202, 060021, Bucharest, Romania

    Mariana Voicescu, Jose M. Calderon-Moreno, Mihai Anastasescu & Daniela C. Culita

  2. Department of Physical Chemistry, University of Bucharest, Bd. Regina Elisabeta 4-12, 030018, Bucharest, Romania

    Sorana Ionescu

  3. Institute of Atomic Physics, National Institute of Materials Physics, 077125, Magurele, Romania

    Valentin S. Teodorescu

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  1. Mariana Voicescu
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  2. Sorana Ionescu
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  3. Jose M. Calderon-Moreno
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  4. Valentin S. Teodorescu
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Correspondence to Mariana Voicescu.

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Voicescu, M., Ionescu, S., Calderon-Moreno, J.M. et al. Tryptophan / Dextran70 Based - Fluorescent Silver Nanoparticles: Synthesis and Physicochemical Properties. J Fluoresc 29, 981–992 (2019). https://doi.org/10.1007/s10895-019-02411-2

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  • DOI: https://doi.org/10.1007/s10895-019-02411-2

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