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The Role of Multiphosphorylated Peptides in Mineralized Tissue Regeneration

  • Special Issue: Peptides in Oral and Dental Research
  • Published:
International Journal of Peptide Research and Therapeutics Aims and scope Submit manuscript

Abstract

Several multiple phosphoseryl-containing proteins have been identified in mineralising tissue and body fluids where they have been proposed to act as nucleators and/or regulators of biomineralisation. In particular, the unique features of the multiphosphorylated caseins from milk and phosphophoryn from dentine enable them to have a role in mineralised tissue regeneration. In this review, three examples of therapeutic applications using multiphosphorylated peptides are described.

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  1. Cooperative Research Centre for Oral Health Science, School of Dental Science, Bio21 Institute, The University of Melbourne, 720 Swanston Street, Victoria, 3010, Australia

    Keith J. Cross, N. Laila Huq, Neil M. O’Brien-Simpson, John W. Perich, Troy J. Attard & Eric C. Reynolds

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  1. Keith J. Cross
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  2. N. Laila Huq
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  3. Neil M. O’Brien-Simpson
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Correspondence to Eric C. Reynolds.

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Cross, K.J., Huq, N.L., O’Brien-Simpson, N.M. et al. The Role of Multiphosphorylated Peptides in Mineralized Tissue Regeneration. Int J Pept Res Ther 13, 479–495 (2007). https://doi.org/10.1007/s10989-007-9105-0

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  • DOI: https://doi.org/10.1007/s10989-007-9105-0

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