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Fungal Keratitis Due to Beauveria bassiana in a Contact Lenses Wearer and Review of Published Reports

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Abstract

Fungal keratitis is a severe ocular infection that primarily affects subjects engaged in outdoor activities. Risk factors include allergic conjunctivitis, previous eye surgery, previous treatment with wide-spectrum antimicrobial agents and corticosteroids and using contact lenses. Corneal infection is usually secondary to trauma involving organic material, which is often the only predisposing factor. Early diagnosis based on clinical examination and microbiological investigation (microscopy, cultures and molecular techniques) is crucial to selecting the appropriate antifungal therapy and prevent progression. We report the case of a patient with keratitis due to Beauveria bassiana, an opportunistic and entomopathogenic filamentous fungus that is used as a biological insecticide and which is a rare cause of corneal infection. We review previous cases reports of B. bassiana keratitis published and its main features to compare with our case, a female occasional agriculture worker who had not suffered any trauma involving organic material. The patient received topical and oral antifungal therapy and debridement surgery, with a satisfactory outcome.

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Authors and Affiliations

  1. Servicio de Microbiología, Hospital Universitario Virgen de las Nieves, Instituto de Investigación Biosanitaria ibs, Granada, Spain

    Ana Lara Oya, María Dolores Rojo Martín, Consuelo Miranda Casas & José María Navarro Marí

  2. Servicio de Oftalmología, Hospital Universitario Virgen de las Nieves, Granada, Spain

    María Eloisa Medialdea Hurtado, Antonia Aguilera Pérez, Marina Rubio Prats & Santiago Medialdea Marcos

  3. Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain

    Ana Alastruey-Izquierdo

Authors
  1. Ana Lara Oya
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  2. María Eloisa Medialdea Hurtado
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  3. María Dolores Rojo Martín
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  4. Antonia Aguilera Pérez
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  5. Ana Alastruey-Izquierdo
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  6. Consuelo Miranda Casas
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  8. Santiago Medialdea Marcos
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  9. José María Navarro Marí
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Correspondence to Ana Lara Oya.

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Lara Oya, A., Medialdea Hurtado, M.E., Rojo Martín, M.D. et al. Fungal Keratitis Due to Beauveria bassiana in a Contact Lenses Wearer and Review of Published Reports. Mycopathologia 181, 745–752 (2016). https://doi.org/10.1007/s11046-016-0027-2

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  • DOI: https://doi.org/10.1007/s11046-016-0027-2

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