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The synthesis of N-ethyl-n-butylamine by amines disproportionation

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Abstract

A synthesis of N-ethyl-n-butylamine with simple separation method in a fixed-bed reactor using CuO–NiO–PtO/γ-Al2O3 as the catalyst was proposed and investigated. The present catalytic system gave high activity and good selectivity, and the reaction conditions such as temperature and liquid hourly space velocity were optimized. Since no water was generated, the protocol proved to be easy to separate, and N-ethyl-n-butylamine was collected at 110 °C by distillation. The yield and the purity were 60.7 and 99.5 %, respectively.

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Acknowledgments

This work was supported by the National Natural Science Foundation of China (No. 21006087), the Natural Science Foundation of the Zhejiang Province (Y4100147, Y4100544), the Science and Technology Research Fund of Quzhou City (20101056), the Fundamental Research Funds for the Central Universities (2011QNA4018), and the Key Innovation Group of Zhejiang Province (2009R50002).

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Authors and Affiliations

  1. State Key Laboratory of Chemical Engineering, Zhejiang University, Hangzhou, People’s Republic of China

    Lu-feng Xu, Jia-min Huang, Chao Qian, Xin-zhi Chen & Chao-hong He

  2. Department of Chemical and Biological Engineering, Zhejiang University, Hangzhou, 310027, People’s Republic of China

    Lu-feng Xu, Jia-min Huang, Chao Qian, Xin-zhi Chen & Chao-hong He

  3. College of Chemical and Materials Engineering, Quzhou College, Quzhou, 324000, People’s Republic of China

    Lu-feng Xu

  4. Zhejiang Jianye Chemical Co., Ltd., Hangzhou, 311600, People’s Republic of China

    Lie Feng & Yun-bin Chen

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  1. Lu-feng Xu
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  2. Jia-min Huang
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  3. Chao Qian
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  4. Xin-zhi Chen
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  5. Lie Feng
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Correspondence to Xin-zhi Chen.

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Xu, Lf., Huang, Jm., Qian, C. et al. The synthesis of N-ethyl-n-butylamine by amines disproportionation. Res Chem Intermed 39, 2697–2704 (2013). https://doi.org/10.1007/s11164-012-0790-8

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  • DOI: https://doi.org/10.1007/s11164-012-0790-8

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