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Novel routes to N-amino-1H-pyrrolo[2,3-b]pyridines from α-hydroxyarylalkyl ketones and hydrazines

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Abstract

Treatment of 3-hydroxy-3-(3-pyridyl)butan-2-one hydrazone with polyphosphoric acid gave 1-amino-2,3-dimethyl-1H-pyrrolo[2,3-b]pyridine. An analogous reaction with 2,4-dinitrophenylhydrazone of the same ketone yielded 1-(2,4-dinitrophenyl)-3-methyl-4-(3-pyridyl)pyrazole.

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Authors and Affiliations

  1. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation

    Yu. B. Chudinov, S. B. Gashev, S. I. Firgang & V. V. Semenov

Authors
  1. Yu. B. Chudinov
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  2. S. B. Gashev
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  3. S. I. Firgang
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  4. V. V. Semenov
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Corresponding author

Correspondence to V. V. Semenov.

Additional information

Dedicated to Academician V. A. Tartakovsky on the occasion of his 75th birthday.

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 8, pp. 1552–1556, August, 2007.

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Chudinov, Y.B., Gashev, S.B., Firgang, S.I. et al. Novel routes to N-amino-1H-pyrrolo[2,3-b]pyridines from α-hydroxyarylalkyl ketones and hydrazines. Russ Chem Bull 56, 1612–1616 (2007). https://doi.org/10.1007/s11172-007-0252-4

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  • DOI: https://doi.org/10.1007/s11172-007-0252-4

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