Abstract
The proposed study is an attempt to perceive theoretically the heat transfer phenomenon in the flow of temperature-dependent viscous blood through microvessels internally surrounded by a thin layer of endothelial glycocalyx at the wall. While flowing through microvessels, the blood separates into erythrocytes suspended fluid and cell-depleted fluid into core and peripheral regions respectively. Therefore, to best represent the flow of human blood in microvessels, it has been modeled as a two-fluid. Erythrocytes appearing in the core stimulates the non-Newtonian behavior of the fluid is manifested here by Herschel-Bulkley fluid with temperature-dependent viscosity. The plasma surrounded over the blood cells in the peripheral layer is expressed as a Newtonian fluid with constant viscosity. An added advantage of utilizing the Brinkman-Forchheimer equation to govern the flow through the layer of endothelial glycocalyx (EGL) is that it is credible for both small and large Darcy numbers (permeability). Linear approximation of the Reynolds, viscosity model is exercised to obtain the analytical solutions for the governing equations of Herschel-Bulkley fluid flowing through the core region. In the non-porous peripheral region, the analytical solutions have been obtained for Newtonian fluid with constant viscosity directly and in the porous peripheral region, the Brinkman-Forchheimer equation is solved using regular perturbation for large Darcy number and singular perturbation with a matched asymptotic condition for small Darcy number. Analytical expressions for the velocity, flow rate, flow impedance, and temperature field have been obtained for the different regions. Graphical analysis revealing significant results regarding the variable viscosity, thermal conductivity, Grashof number, Forchheimer number, Richardson number, and permeability on the hemodynamical variables are conducted and results are discussed in detail. The study concludes that an EGL adjacent to the vessel wall increase the resistance to blood flow. The notable discovery of the study is that the temperature parameters influence all the quantities and therefore establish that the temperature-dependent viscosity plays a vital role in medical treatments involving temperature variation such as chemotherapy.
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Abbreviations
- r, z :
-
Radial and axial coordinates, respectively
- \(h_1, h\) :
-
Core and peripheral region thickness, respectively
- \(w_H, w_N, w_B\) :
-
Axial velocities in core, intermediate and porous regions, respectively
- \(R_p, w_p\) :
-
Radius and velocity of the fluid in plug core region, respectively
- \(W_0\) :
-
Characteristic velocity
- n :
-
Herschel-Bulkley fluid parameter
- \(p_H, p_N, p_B\) :
-
Pressures in core, intermediate and porous regions, respectively
- \(T_H, T_N, T_B\) :
-
Temperatures in core, intermediate and porous regions, respectively
- \(K_H, K_N\) :
-
Thermal conductivities in core and plasma regions, respectively
- \(K_0\) :
-
Thermal conductivity ratio
- \(Q_H, Q_N\) :
-
Constant heat absorptions in core and plasma regions, respectively
- \(p_s\) :
-
Pressure gradient
- \(Q_s\) :
-
Rate of fluid flow (volumetric flow rate)
- \(R_1, R_2, R_3\) :
-
Tube radius in core, intermediate and porous regions, respectively
- \(T_w, T_\infty\) :
-
Temperature at wall and ambient temperature, respectively
- Gr :
-
Grashof number (free convection parameter)
- Re :
-
Reynolds number
- Ri :
-
Richardson number (i.e., \(Ri=Gr/Re^2\))
- F :
-
Forchheimer number
- S :
-
Dimensionless shape parameter in porous medium defined in Eq. (4)
- \(C_F\) :
-
Inertial coefficient
- k :
-
Permeability of the porous medium (i.e., Darcy number Da)
- g :
-
Gravitational force
- \(\text {PW}\) :
-
Porous region near the vessel wall
- \(\text {NF, PL}\) :
-
Newtonian and Power-law fluids, respectively
- \(\text {BP, HB}\) :
-
Bingham-plastic and Herschel-Bulkley fluids, respectively
- \(\text {TFM}\) :
-
Two-fluid model
- \(\text {SDN, LDN}\) :
-
Small Darcy number and large Darcy number, respectively
- Phase-I:
-
Core region (i.e., \(0<\widetilde{r}\le \widetilde{R}_1\))
- Phase-II:
-
Intermediate region (i.e., \(\widetilde{R}_1\le \widetilde{r}\le \widetilde{R}_2\))
- Phase-III:
-
Porous region (i.e., \(\widetilde{R}_2\le \widetilde{r}\le \widetilde{R}_3\))
- \(\phi\) :
-
Azimuthal angle
- \(\alpha\) :
-
Viscosity index
- \(\alpha _p\) :
-
Porosity parameter
- \(\tau _H\) :
-
Shear stress of Herschel-Bulkley fluid
- \(\tau _y\) :
-
Yield stress
- \(\theta\) :
-
Dimensionless yield stress
- \(\theta _H, \theta _N, \theta _B\) :
-
Temperatures in core, intermediate and porous regions, respectively
- \(\rho _H, \rho _N\) :
-
Density of Herschel-Bulkley and Newtonian fluids, respectively
- \(\rho _0\) :
-
Density ratio
- \(\gamma _1,\gamma _2\) :
-
Mean absorption coefficients
- \(\gamma _0\) :
-
Mean absorption coefficients ratio
- \(\gamma\) :
-
Coefficient of the volume expansion due to the temperature
- \(\tau _w\) :
-
Shear stress at wall
- \(\mu (\theta _H)\) :
-
Variable viscosity of core region fluid
- \(\mu _H, \mu _N\) :
-
Constant viscosity coefficients of HB and NF, respectively
- \(\mu _E\) :
-
Effective viscosity of the porous medium
- \(\lambda _1\) :
-
Viscosity ratio parameter (\(\lambda _1^2=\widetilde{\mu }_E/\widetilde{\mu }_N\))
- \(\lambda _s\) :
-
Flow resistance (impedance)
- p :
-
Plug flow value (for \(w_p, R_p\))
- s :
-
Steady flow value (for \(p_s, Q_s, \lambda _s\))
- H :
-
Symbolizes for Herschel-Bulkley fluid (for \(w_H, \theta _H, \tau _H, Q_H, K_H, \mu _H, \rho _H, p_H\))
- N :
-
Symbolizes for Newtonian fluid (for \(w_N, \theta _N, Q_N, K_N, \mu _N, \rho _N, p_N\))
- B :
-
Symbolizes for Brinkman-Forchheimer region (for \(w_B, p_B\))
- w :
-
Value at vessel wall (for \(\tau _w, T_w\))
- y :
-
Value at yield stress (for \(\tau _y\))
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Chauhan, S.S., Shah, P.D. & Tiwari, A. Analytical Study of the Effect of Variable Viscosity and Heat Transfer on Two-Fluid Flowing through Porous Layered Tubes. Transp Porous Med 142, 641–668 (2022). https://doi.org/10.1007/s11242-022-01765-9
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DOI: https://doi.org/10.1007/s11242-022-01765-9