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Inhibition of five natural products from Chinese herbs on the growth of Chattonella marina

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Abstract

The effects of five natural products from Chinese herbs including evodiamine, curcumin, 4-methoxysalicylaldehyde, esculin hydrate, and gramine on the growth of Chattonella marina, one of the most noxious red tide algae, were observed. Among them, gramine exhibited the highest inhibitory rate with LC50, 96h of 0.51 mg/l. After exposure to gramine, the activities of superoxide dismutase (SOD) and catalase (CAT), and content of malondialdehyde (MDA) increased in C. marina, suggesting that gramine could induce microalgae oxidative stress. In addition, chlorophyll a and the maximum quantum yield of photosynthesis (Fv/Fm) decreased following exposure to gramine, indicating the inhibition of photosynthesis activity in the microalgae. Combined with the fast inhibition against the algal cells and environmentally friendly character of gramine, we proposed that gramine might be a potential algaecide against marine harmful algae and that the oxidative damage and photosynthesis inhibition might be responsible for the toxicity of gramine on harmful algae.

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Acknowledgments

This work was supported by the Technical Extension Special Project of Guangdong Marine Fisheries Service (A201201K01), the Science and Technology Projects of Guangdong Province (2009B030803042), and Guangzhou Environmental Protection Project (2008–07).

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Authors and Affiliations

  1. Key Laboratory of Aquatic Eutrophication and Control of Harmful Algal Blooms of Guangdong Higher Education Institute, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China

    Fei Liu, Zheng-Bing He, Hong-Ye Li, Jie-Sheng Liu & Wei-Dong Yang

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  1. Fei Liu
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  2. Zheng-Bing He
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  3. Hong-Ye Li
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  4. Jie-Sheng Liu
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Correspondence to Jie-Sheng Liu or Wei-Dong Yang.

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Liu, F., He, ZB., Li, HY. et al. Inhibition of five natural products from Chinese herbs on the growth of Chattonella marina . Environ Sci Pollut Res 23, 17793–17800 (2016). https://doi.org/10.1007/s11356-016-6755-5

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