Abstract
Amorphous silicon carbide (a-SiC:H) thin films were synthesized using trichloromethylsilane by a hot wire chemical vapor deposition process. The deposited films were characterized by Fourier transform infrared spectroscopy (FTIR), Raman spectroscopy, x-ray diffraction and x-ray photoelectron spectroscopy to confirm its chemical bonding, structural network and composition of the a-SiC:H films. The optical microscopy images reveal that hydrogen dilution increased the surface roughness and pore density of a-SiC:H thin film. The Raman spectroscopy and FTIR spectra reveal chemical network consisting of Si-Si, C-C and Si-C bonds, respectively. The XRD spectroscopy and Raman spectroscopy indicate a-SiC:H still has short-range order. In addition, in vitro cytotoxicity test ensures the behavior of cell–semiconductor hybrid to monitor the proper coordination. The live–dead assays and MTT assay reveal an increase in green nucleus cell, and cell viability is greater than 88%, respectively, showing non-toxic nature of prepared a-SiC:H film. Moreover, the result indicated by direct contact assay, and cell prefers to adhere and proliferate on a-SiC:H thin films having a positive effect as artificial heart valve coating material.
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Acknowledgment
The authors thank Biogenic Research Centre, Thiruvananthapuram, Kerala, India, for helping with the various biological tests. Our sincere thanks go to National Centre for Cell Science, Pune, India, for providing us fibroblast cell. We are grateful to the Department of Biotechnology (DBT) for financial assistance vide Project No (BCIL/NER-BPMC/2012/650). Mr. Umesh Rizal acknowledged the financial support from JRF scheme under the Department of Biotechnology, Government of India.
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Rizal, U., Swain, B.S., Rameshbabu, N. et al. Biocompatibility of Hydrogen-Diluted Amorphous Silicon Carbide Thin Films for Artificial Heart Valve Coating. J. of Materi Eng and Perform 27, 2679–2686 (2018). https://doi.org/10.1007/s11665-018-3198-9
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DOI: https://doi.org/10.1007/s11665-018-3198-9