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Performance-driven design of Biocompatible Mg alloys

  • Corrosion in Biological Environments
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Abstract

Magnesium (Mg) and its alloys provide numerous benefits as a resorptive biomaterial and present the very real possibility of replacing current metallic implant materials in a variety of roles. The development of suitable biodegradable implant alloys is a multidisciplinary challenge, since alloy design must be confined to a range of alloying additions that are biologically nontoxic, whilst still providing the requisite mechanical properties. This leaves a small number of compatible elements that can provide benefits when alloyed with Mg, including calcium (Ca) and zinc (Zn). To date, although a range of different Mg alloys have been investigated both in vitro and in vivo, little work has been performed to characterize the relationship between the composition of Mg alloys, their corrosion and resulting mechanical properties over time. Consequently it is crucial to understand how these properties may be related if alloys are to be successfully screened for implantation in the body.

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Authors and Affiliations

  1. Department of Materials Engineering, Monash University, Clayton, 3800, Victoria, Australia

    Nicholas T. Kirkland, Chris H.J. Davies & Nick Birbilis

  2. BioMATE Group, Mechanical Engineering Department, University of Canterbury, Engineering Road, Ilam, Christchurch, 8041, New Zealand

    Nicholas T. Kirkland & Mark P. Staiger

  3. Research School of Engineering, The Australian National University, Acton, 0200, Australian Capital Territory, Australia

    David Nisbet

Authors
  1. Nicholas T. Kirkland
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  2. Mark P. Staiger
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  3. David Nisbet
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  4. Chris H.J. Davies
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  5. Nick Birbilis
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Correspondence to Nick Birbilis.

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Kirkland, N.T., Staiger, M.P., Nisbet, D. et al. Performance-driven design of Biocompatible Mg alloys. JOM 63, 28–34 (2011). https://doi.org/10.1007/s11837-011-0089-z

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