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Products of gut-microbial tryptophan metabolism inhibit the steroid hormone-synthesizing cytochrome P450 11A1

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Acknowledgments

We thank Dr. Yogan Khatri for scientific advice.

Author contributions

AG. conceived the study and designed experiments. A.M. performed experiments. J.N. performed cell culture experiments. A.M. and A.G. wrote the manuscript, with contributions from R.B. R.B. participated in the interpretation and discussion of experimental results.

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    Authors and Affiliations

    1. Institute of Biochemistry, Campus B 2.2, Saarland University, 66123, Saarbrücken, Germany

      A. Mosa, A. Gerber, J. Neunzig & Rita Bernhardt

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    1. A. Mosa
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    2. A. Gerber
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    3. J. Neunzig
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    4. Rita Bernhardt
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    Corresponding author

    Correspondence to Rita Bernhardt.

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    The authors declare no conflict of interest.

    Additional information

    Mosa and Gerber contributed equally to this study.

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    Mosa, A., Gerber, A., Neunzig, J. et al. Products of gut-microbial tryptophan metabolism inhibit the steroid hormone-synthesizing cytochrome P450 11A1. Endocrine 53, 610–614 (2016). https://doi.org/10.1007/s12020-016-0874-0

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    • DOI: https://doi.org/10.1007/s12020-016-0874-0

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