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Treatment of autonomous ovarian follicular cyst with long-term anastrozole therapy

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Abstract

Functional follicular ovarian cysts are frequently reported in girls with peripheral precocious puberty (PP). These cysts are usually self-limiting and resolve spontaneously. Several drugs like antiestrogens (tamoxifen) and new aromatase inhibitors are seldom used for treatment. Here we report a girl with peripheral PP who presented with unilateral enlargement of the ovary and a recurrent autonomous ovarian cyst. No skin pigmentation or bone anomaly was noted. The patient was successfully treated with anastrozole, a highly selective aromatase inhibitor. No adverse reaction was noted. Anastrozole is a safe and tolerable drug especially used to suppress estrogen action.

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Correspondence to Ozlem Engiz.

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Engiz, O., Berberoglu, M., Siklar, Z. et al. Treatment of autonomous ovarian follicular cyst with long-term anastrozole therapy. Indian J Pediatr 76, 950–951 (2009). https://doi.org/10.1007/s12098-009-0190-2

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  • DOI: https://doi.org/10.1007/s12098-009-0190-2

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