Abstract
Typical hypnotic drugs, such as barbitals and glutethimide, have a cyclic imide (-CO-NH-CO-) moiety. The N-Cbz-α-aminoglutarimidooxy carboxylate derivatives, which we previously showed exhibit moderate anticonvulsant activities, also have a cyclic imide (-CO-N-CO-) moiety. This structural similarity prompted us to examine the hypnotic activities of the N-Cbz-α-aminoglutarimidooxy carboxylate derivatives, and we describe their moderate hypnotic activities here.
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Byun, A., Park, J.Y., Moon, K.H. et al. Synthesis and hypnotic activities of N-Cbz-α-aminoglutarimidooxy carboxylate derivatives. Arch. Pharm. Res. 31, 834–837 (2008). https://doi.org/10.1007/s12272-001-1234-1
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DOI: https://doi.org/10.1007/s12272-001-1234-1