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A new 9,11-secosterol with a 1,4-quinone from a Korean marine sponge Ircinia sp.

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Abstract

An intensive investigation of chemical components for Ircinia sp. led to the isolation of a new 9,11-secosterol. The chemical structure of this compound was elucidated based on the interpretation of NMR and MS spectroscopic data. The isolated compound exhibited antibacterial activities against Staphylococcus epidermidis and Bacillus subtilis with MIC values of 6.3 and 25 μg ml−1, respectively.

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Acknowledgments

This work was supported by Suncheon Research Center for Natural Medicines. I. Yang was in part supported by the BK21 program, Ministry of Education, Korea.

Conflict of interest

The authors declare that they have no conflict of interest.

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    Authors and Affiliations

    1. Center for Marine Natural Products and Drug Discovery, School of Earth and Environmental Sciences, Seoul National University, NS-80, Seoul, 151-747, Korea

      Inho Yang & Heonjoong Kang

    2. College of Pharmacy, Yeungnam University, Gyeongsan, 712-749, Korea

      Hyukjae Choi

    3. Department of Chemistry and Nano Science, Global Top5 Program, Ewha Womans University, Seoul, 120-750, Korea

      Sang-Jip Nam

    4. Research Institute of Oceanography, Seoul National University, NS-80, Seoul, 151-747, Korea

      Heonjoong Kang

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    1. Inho Yang
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    2. Hyukjae Choi
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    Correspondence to Sang-Jip Nam or Heonjoong Kang.

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    Inho Yang and Hyukjae Choi have contributed equally to this work.

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    Yang, I., Choi, H., Nam, SJ. et al. A new 9,11-secosterol with a 1,4-quinone from a Korean marine sponge Ircinia sp.. Arch. Pharm. Res. 38, 1970–1974 (2015). https://doi.org/10.1007/s12272-015-0620-9

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    • DOI: https://doi.org/10.1007/s12272-015-0620-9

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