Skip to main content

Advertisement

Log in

Psychological Interventions for Coronary Heart Disease: Cochrane Systematic Review and Meta-analysis

  • Published:
International Journal of Behavioral Medicine Aims and scope Submit manuscript

Abstract

Background

Depression and anxiety are common in cardiac patients, and psychological interventions may also be used as part of general cardiac rehabilitation programs.

Purpose

This study aims to estimate effects of psychological interventions on mortality and psychological symptoms in this group, updating an existing Cochrane Review.

Method

Systematic review and meta-regression analyses of randomized trials evaluating a psychological treatment delivered by trained staff to patients with a diagnosed cardiac disease, with a follow-up of at least 6 months, were used.

Results

There was no strong evidence that psychological intervention reduced total deaths, risk of revascularization, or non-fatal infarction. Psychological intervention did result in small/moderate improvements in depression and anxiety, and there was a small effect for cardiac mortality.

Conclusion

Psychological treatments appear effective in treating patients with psychological symptoms of coronary heart disease. Uncertainty remains regarding the subgroups of patients who would benefit most from treatment and the characteristics of successful interventions.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

References

  1. Chung MC, Berger Z, Jones R, Rudd H. Posttraumatic stress disorder and general health problems following myocardial infarction (Post-MI PTSD) among older patients: the role of personality. Int J Geriatr Psychiatr. 2006;21(12):1163–74.

    Article  Google Scholar 

  2. Krishnan KRR, Delong M, Kraemer H, et al. Comorbidity of depression with other medical diseases in the elderly. Biol Psychiatry. 2002;52(6):559–88.

    Article  PubMed  Google Scholar 

  3. Diener E, Chan MY. Happy people live longer: subjective well-being contributes to health and longevity. Appl Psychol Health Well-Being. 2011;3(1):1–43.

    Article  Google Scholar 

  4. Stice E. Risk and maintenance factors for eating pathology: a meta-analytic review. Psychol Bull. 2002;128(5):825.

    Article  PubMed  Google Scholar 

  5. Hopko DR, Mullane CM. Exploring the relation of depression and overt behavior with daily diaries. Behav Res Ther. 2008;46(9):1085–9.

    Article  PubMed  Google Scholar 

  6. Halaris A. Comorbidity between depression and cardiovascular disease. Int Angiol. 2009;28(2):92–9.

    CAS  PubMed  Google Scholar 

  7. Hemingway H, Marmot M. Psychosocial factors in the aetiology and prognosis of coronary heart disease: systematic review of prospective cohort studies. BMJ. 1999;318(7196):1460–7.

    Article  CAS  PubMed  Google Scholar 

  8. Cesari M, Penninx BBWJH, Newman AAB, et al. Inflammatory markers and onset of cardiovascular events. Circulation. 2003;108(19):2317–22. Available at: http://circ.ahajournals.org/content/108/19/2317.short. Accessed February 29, 2012.

    Article  CAS  PubMed  Google Scholar 

  9. Hansson GK. Immune mechanisms in atherosclerosis. Arterioscler Thromb Vasc Biol. 2001;21(12):1876–90. Available at: http://atvb.ahajournals.org/cgi/content/abstract/21/12/1876. Accessed March 26, 2012.

    Article  CAS  PubMed  Google Scholar 

  10. Mendall MA, Patel P, Asante M, et al. Relation of serum cytokine concentrations to cardiovascular risk factors and coronary heart disease. Heart. 1997;78(3):273–7.

    CAS  PubMed  Google Scholar 

  11. Martin RA. Humor, laughter, and physical health: methodological issues and research findings. Psychol Bull. 2001;127(4):504.

    Article  CAS  PubMed  Google Scholar 

  12. Pasic J, Levy WC, Sullivan MD. Cytokines in depression and heart failure. Psychosom Med. 2003;65(2):181–93.

    Article  PubMed  Google Scholar 

  13. Greaves C, Sheppard K, Abraham C, et al. Systematic review of reviews of intervention components associated with increased effectiveness in dietary and physical activity interventions. BMC Publ Health. 2011;11(1):119.

    Article  Google Scholar 

  14. Lespérance F, Frasure-Smith N. Depression in patients with cardiac disease: a practical review. J Psychosom Res. 2000;48:379–91.

    Article  PubMed  Google Scholar 

  15. Jolly K, Bradley F, Sharp S, Smith H, Mant D. Follow-up care in general practice of patients with myocardial infarction or angina pectoris: initial results of the SHIP trial. Southampton Heart Integrated Care Project. Fam Pract. 1998;15(6):548–55.

    Article  CAS  PubMed  Google Scholar 

  16. Black JL, Allison TG, Williams DE, Rummans TA, Gau GT. Effect of intervention for psychological distress on rehospitalization rates in cardiac rehabilitation patients. Psychosomatics. 1998;39(2):134–43.

    Article  CAS  PubMed  Google Scholar 

  17. Burnett-Zeigler I, Zivin K, Ilgen M, et al. Depression treatment in older adult veterans. Am J Geriatr Psychiatr. 2010.

  18. Cepoiu M, McCusker J, Cole MG, et al. Recognition of depression by non-psychiatric physicians—a systematic literature review and meta-analysis. J Gen Intern Med. 2008;23(1):25–36.

    Article  PubMed Central  PubMed  Google Scholar 

  19. Welton NJ, Caldwell DM, Adamopoulos E, Vedhara K. Mixed treatment comparison meta-analysis of complex interventions: psychological interventions in coronary heart disease. Am J Epidemiol. 2009;169(9):1158.

    Article  PubMed  Google Scholar 

  20. Rees K, Bennett P, West R, Davey SG, Ebrahim S. Psychological interventions for coronary heart disease. Cochrane Database Syst Rev. 2004;2:CD002902.

    PubMed  Google Scholar 

  21. DeBusk RF, Miller NH, Superko R, et al. A case-management system for coronary risk factor modification after acute myocardial infarction. Ann Intern Med. 1994;120:721–9.

    Article  CAS  PubMed  Google Scholar 

  22. Erdman RAM, Duivenvoorden HJ. Psychologic evaluation of a cardiac rehabilitation program: a randomized clinical trial in patients with myocardial infarction. J Cardiopulm Rehabil Prev. 1983;3(10):696–704.

    Google Scholar 

  23. Fridlund B, Hogstedt B, Lidell E, Larsson PA. Recovery after myocardial infarction: effects of a caring rehabilitation programme. Scand J Caring Sci. 1991;5(1):23–32.

    Article  CAS  PubMed  Google Scholar 

  24. Linden W, Phillips MJ, Leclerc J. Psychological treatment of cardiac patients: a meta-analysis. Eur Hear J. 2007;28(24):2972–84.

    Article  Google Scholar 

  25. ENRICHD. Enhancing Recovery in Coronary Heart Disease (ENRICHD) study intervention: rationale and design. Psychosom Med. 2001;63(5):747–55.

    Google Scholar 

  26. Butler A, Chapman J, Forman E, Beck A. The empirical status of cognitive-behavioral therapy: a review of meta-analyses. Clin Psychol Rev. 2006;26(1):17–31.

    Article  PubMed  Google Scholar 

  27. Abraham C, Michie S. A taxonomy of behavior change techniques used in interventions. Heal Psychol. 2008;27(3):379.

    Article  Google Scholar 

  28. Wilson C, Huston T, Koval J, et al. SCIRehab Project series: the psychology taxonomy. J Spinal Cord Med. 2009;32(3):319.

    PubMed  Google Scholar 

  29. Higgins JPT, Altman DG, Gøtzsche PC, et al. The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ (Clinical research ed). 2011;343:d5928. Available at: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3196245&tool=pmcentrez&rendertype=abstract. Accessed March 19, 2012.

    Article  Google Scholar 

  30. Cochrane. Preferred method for handling continuous variables. 2003. Available at: http://heart.cochrane.org/resources-review-authors.

  31. Follmann D, Elliot P, Suh I, Cutler J. Variance imputation for overviews of clinical trials with continuous response. J Clin Epidemiol. 1992;45:769–73.

    Article  CAS  PubMed  Google Scholar 

  32. Hersen M, Hilsenroth MJ, Segal DL. Comprehensive handbook of psychological assessment. Hoboken: Wiley; 2004.

    Google Scholar 

  33. Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple graphical test. BMJ. 1997;315:629–34.

    Article  CAS  PubMed  Google Scholar 

  34. Brown MA, Munford AM, Munford PR. Behavior therapy of psychological distress in patients after myocardial infarction or coronary bypass. J Cardpulm Rehabil. 1993;13(3):201–10.

    Article  Google Scholar 

  35. Burgess AW, Lerner DJ, d’ Agostino RB, Vokonas PS. A randomized control trial of cardiac rehabilitation. Soc Sci Med. 1987;24(4):359–70.

    Article  CAS  PubMed  Google Scholar 

  36. Cowan MJ, Pike KC, Kogan BH. Psychosocial nursing therapy following sudden cardiac arrest: impact on two-year survival. Nurs Res. 2001;50(2):68–76.

    Article  CAS  PubMed  Google Scholar 

  37. Elderen-van-Kemenade T, Maes S, van-den Broek Y. Effects of a health education programme with telephone follow-up during cardiac rehabilitation. Br J Clin Psychol. 1994;33(3):367–78.

    Article  PubMed  Google Scholar 

  38. Gallacher JEJ, Hopkinson CA, Bennett P, Burr ML, Elwood PC. Effect of stress management on angina. Psychol Heal. 1997;12(4):523–32.

    Article  Google Scholar 

  39. HofmanBang C, Lisspers J, Nordlander R, et al. Two-year results of a controlled study of residential rehabilitation for patients treated with percutaneous transluminal coronary angioplasty—a randomized study of a multifactorial programme. Eur Hear J. 1999;20(20):1465–74.

    Article  CAS  Google Scholar 

  40. Ibrahim MA, Feldman JG, Sultz HA, et al. Management after myocardial infarction: a controlled trial of the effect of group psychotherapy. Int J Psychiatry Med. 1974;5(3):253–68.

    Article  CAS  PubMed  Google Scholar 

  41. Jones DA, West RR. Psychological rehabilitation after myocardial infarction: multicentre randomised controlled trial. BMJ. 1996;313(7071):1517–21.

    Article  CAS  PubMed  Google Scholar 

  42. Oldenburg B, Perkins RJ, Andrews G. Controlled trial of psychological intervention in myocardial infarction. J Consult Clin Psychol. 1985;53(6):852–9.

    Article  CAS  PubMed  Google Scholar 

  43. Rahe RH, Ward HW, Hayes V. Brief group therapy in myocardial infarction rehabilitation: three- to four-year follow-up of a controlled trial. Psychosom Med. 1979;51(3):229–42.

    Google Scholar 

  44. Friedman M, Thoresen CE, Gill JJ, et al. Feasibility of altering type A behaviour pattern after myocardial infarction. Circulation. 1982;66(1):83–92.

    Article  CAS  PubMed  Google Scholar 

  45. Stern MJ, Gorman PA, Kaslow L. The group counseling v exercise therapy study. A controlled intervention with subjects following myocardial infarction. Arch Intern Med. 1983;143(9):1719–25.

    Article  CAS  PubMed  Google Scholar 

  46. Van-Dixhoorn JJ, Duivenvoorden HJ. Effect of relaxation therapy on cardiac events after myocardial infarction: a 5-year follow-up study. J Cardpulm Rehabil. 1999;19(3):178–85.

    Article  CAS  Google Scholar 

  47. Appels A, Bar F, van der Pol G, et al. Effects of treating exhaustion in angioplasty patients on new coronary events: results of the randomized exhaustion intervention trial (EXIT). Psychosom Med. 2005;67(2):217–23.

    Article  PubMed  Google Scholar 

  48. Claesson M, Birgander L, Lindahl B, et al. Women’s hearts: stress management for women with ischemic heart disease: explanatory analyses of a randomized controlled trial. J Cardpulm Rehabil. 2005;25(2):93–102.

    Article  Google Scholar 

  49. Koertge J, Janszky I, Sundin O, et al. Effects of a stress management program on vital exhaustion and depression in women with coronary heart disease: a randomized controlled intervention study. J Intern Med. 2008;263(3):281–93.

    Article  CAS  PubMed  Google Scholar 

  50. Mayou R, Thompson D, Clements A, et al. Guideline-based early rehabilitation after myocardial infarction: a pragmatic randomised controlled trial. J Psychosom Res. 2002;52(2):89–95.

    Article  PubMed  Google Scholar 

  51. McLaughlin T, Aupont O, Bambauer K, et al. Improving psychologic adjustment to chronic illness in cardiac patients: the role of depression and anxiety. J Gen Intern Med. 2005;20(12):1084–90.

    Article  PubMed Central  PubMed  Google Scholar 

  52. Michalsen A, Grossman P, Lehmann N, et al. Psychological and quality-of-life outcomes from a comprehensive stress reduction and lifestyle program in patients with coronary artery disease: results of a randomized trial. Psychother Psychosom. 2005;74(6):344–52.

    Article  PubMed  Google Scholar 

  53. Peng J, Jiang LJ. Psychotherapy on negative emotions for the incidence of ischemia-related events in patients with coronary heart disease. Chin J Clin Rehabil. 2005;9(4):38–9.

    Google Scholar 

  54. Sebregts EHWJ, Falger PRJ, Appels A, Kester ADM, Bär FWHM. Psychological effects of a short behavior modification program in patients with acute myocardial infarction or coronary artery bypass grafting: a randomized controlled trial. J Psychosom Res. 2005;58(5):417–24.

    Article  PubMed  Google Scholar 

  55. Dunn AL, Trivedi MH, Kampert JB, Clark CG, Chambliss HO. Exercise treatment for depression: efficacy and dose response. Am J Prev Med. 2005;28(1):1–8.

    Article  PubMed  Google Scholar 

  56. Kuper H, Nicholson A, Kivimaki M, et al. Evaluating the causal relevance of diverse risk markers: horizontal systematic review. BMJ. 2009;339:b4265.

    Article  PubMed Central  PubMed  Google Scholar 

  57. Carney RM, Freedland KE, Miller GE, Jaffe AS. Depression as a risk factor for cardiac mortality and morbidity: a review of potential mechanisms. J Psychosom Res. 2002;53:897–902.

    Article  PubMed  Google Scholar 

  58. Jacobson NS, Dobson KS, Truax PA, et al. A component analysis of cognitive—behavioral treatment for depression. J Consult Clin Psychol. 1996;64(2):295–304.

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgments

We would like to acknowledge all the authors who provided additional information on request and Cornelia Junghans for Russian and German translations. Ben Whalley was supported by an ESRC fellowship (PTA-026-27-2113). We also wish to acknowledge the authors of the original Cochrane review as follows: Karen Rees, Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, UK; Philippa Davies, Academic Unit of Psychiatry, School of Social and Community Medicine, University of Bristol, Bristol, UK; Paul Bennett, Department of Psychology, University of Swansea, Swansea, UK; Shah Ebrahim, Department of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK; Zulian Liu, Peninsula Medical School, University of Exeter, Exeter, UK; Robert West, Wales Heart Research Institute, Cardiff University, Cardiff, UK; and Tiffany Moxham, Wimberly Library, Florida Atlantic University, Boca Raton, Florida, USA. The study was funded by a UK National Institute for Health Research Cochrane Programme Grant (CPG510).

Conflict of Interest

None.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Rod S. Taylor.

Additional information

A version of this article has been accepted and published by the Cochrane Review Group, December 2011 [citation, Whalley B, Rees K, Davies P, Bennett P, Ebrahim S, Liu Z, West R, Moxham T, Thompson DR, Taylor RS. Psychological interventions for coronary heart disease. Cochrane Database of Systematic Reviews. 2011;8(art no CD002902). doi:10.1002/14651858.CD002902.pub3].

Rights and permissions

Reprints and permissions

About this article

Cite this article

Whalley, B., Thompson, D.R. & Taylor, R.S. Psychological Interventions for Coronary Heart Disease: Cochrane Systematic Review and Meta-analysis. Int.J. Behav. Med. 21, 109–121 (2014). https://doi.org/10.1007/s12529-012-9282-x

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12529-012-9282-x

Keywords

Navigation