Abstract
Lipidic cubic phase (LCP) structures have been used for stabilisation and crystallisation of membrane proteins and show promising properties as drug carriers. In this mini-review, we present how NMR spectroscopy has played a major role in understanding the physico-chemical properties of LCPs and how recent advances in pulsed field gradient NMR techniques open new perspectives in characterising encapsulated molecules.
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The authors acknowledge the Bio21 NMR Facility for providing the facilities to carry out study of LCPs.
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Rajput, S., Yao, S., Keizer, D.W. et al. NMR spectroscopy of lipidic cubic phases. Biophys Rev 14, 67–74 (2022). https://doi.org/10.1007/s12551-021-00900-y
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DOI: https://doi.org/10.1007/s12551-021-00900-y