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Bronsted Acidic Ionic Liquids (BAILs)-Catalyzed Synthesis of 1,8-Dioxo-Octahydroxanthene and 2,2′-Arylmethylene Bis(3-Hydroxy-5,5-Dimethyl-2-Cyclohexene-1-One) Derivatives Under Eco-Friendly Conditions

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Abstract

A simple and efficient one-pot process for the synthesis of 1,8-dioxo-octahydroxanthene and 2,2′-arylmethylene bis(3-hydroxy-5,5-dimethyl-2-cyclohexene-1-one) derivatives via the Knoevenagel–Michael cascade reactions of aromatic aldehydes and dimedone catalyzed by Bronsted acidic ionic liquids (BAILs) in solvent-free and aqueous conditions is described in this study. These heterocycles were prepared in the presence of Bronsted acidic ionic liquids as a suitable, economical, readily synthesized and eco-friendly catalyst. This method offers several advantages such as high yields, simplicity of the workup, low cost, short reaction times, green conditions and use of a reusable catalyst.

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Acknowledgments

We are thankful to the University of Sistan and Baluchestan Research Council for the partial support of this research.

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, P.O. Box 98135-674, Zahedan, Iran

    Jahanbakhsh Ashtarian, Reza Heydari & Malek-Taher Maghsoodlou

  2. Department of Biology, Science and Arts University, Yazd, Iran

    Afshin Yazdani-Elah-Abadi

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  1. Jahanbakhsh Ashtarian
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  2. Reza Heydari
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Correspondence to Reza Heydari.

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Ashtarian, J., Heydari, R., Maghsoodlou, MT. et al. Bronsted Acidic Ionic Liquids (BAILs)-Catalyzed Synthesis of 1,8-Dioxo-Octahydroxanthene and 2,2′-Arylmethylene Bis(3-Hydroxy-5,5-Dimethyl-2-Cyclohexene-1-One) Derivatives Under Eco-Friendly Conditions. Iran J Sci Technol Trans Sci 44, 51–64 (2020). https://doi.org/10.1007/s40995-019-00786-2

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