Short communication
Immunohistochemical localization of tenascin and fibronectin in the dentine and gingiva of Canis familiaris

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Abstract

Specific, well-characterized antisera to the extracellular matrix glycoprotein tenascin were used. Immunoreactivity was detected in association with dentinal tubules; it was particularly prominent in the tooth crown, and was stronger within matrix than within predentine. In contrast, there was no anti-fibronectin staining in dentinal tubules. In periodontium, anti-tenascin immunoreactivity was stronger in the oral and sulcular gingival epithelia than in the underlying connective tissue, in contrast to the strong staining of connective tissue by anti-fibronectin. The appearance of tenascin immunoreactivity in gingival epithelia indicates that this protein is not exclusively a component of mesenchymal extracellular matrix.

References (37)

  • J.-C Boucaut et al.

    Biologically active synthetic peptides as probes of embryonic development: a competitive peptide inhibitor of fibronectin function inhibits gastrulation in amphibian embryos and neural crest migration in avian embryos

    J. Cell Biol.

    (1984)
  • M.A. Bourdon et al.

    Human glioma-mesenchymal extracellular matrix antigen defined by monoclonal antibody

    Cancer Res.

    (1983)
  • M. Brännström

    Hydrodynamic mechanism in the transmission of pain produced stimuli through the dentine

  • M. Brännström et al.

    The hydrodynamics of the dentine: its possible relationship to dentinal pain

    Int. dent. J.

    (1972)
  • A.L. Bronckers et al.

    Immunohistochemistry of extracellular matrix proteins during various stages of dentinogenesis

    Conn. Tiss. Res.

    (1989)
  • H.-H. Epperlein et al.

    The distribution of fibronectin and tenascin along migratory pathways of the neural crest in the trunk of amphibian embryos

    Development

    (1988)
  • H.P. Erickson et al.

    A six-armed oligomer isolated from cell surface fibronectin preparations

    Nature (Lond.)

    (1984)
  • H.P. Erickson et al.

    Hexabrachion proteins in embryonic chicken tissues and human tumors

    J. Cell Biol.

    (1987)
  • Cited by (4)

    Current address: University of Colorado Health Sciences Center, School of Dentistry, Department of Surgical Dentistry, Denver, CO 80262, U.S.A.

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