Regular articleEquine herpesvirus 5: Comparisons with EHV2 (equine cytomegalovirus), cloning, and mapping of a new equine herpesvirus with a novel genome structure☆
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Genomic diversity and natural recombination of equid gammaherpesvirus 5 isolates
2023, Infection, Genetics and EvolutionDisorders of the Neurologic System
2018, Equine Internal Medicine: Fourth EditionEquine gammaherpesviruses: Perfect parasites?
2013, Veterinary MicrobiologyCitation Excerpt :The genome of EHV-5 is marginally smaller at 179 kbp, and has a distinct class F arrangement without any identical or repeat terminal sequences (Agius et al., 1992). Consistent with the level of sequence homology throughout the genomes of EHV-2 and EHV-5 seen in Southern blots (Agius et al., 1992; Browning and Studdert, 1987b) and genome sequence comparisons (Holloway et al., 1999, 2000; Telford et al., 1993), these viruses share both common and type specific antigens and epitopes (Agius et al., 1994). Intratypic genome heterogeneity within EHV-2 isolates also results in some antigenic variability within EHV-2 strains (Browning and Studdert, 1989; Holloway et al., 2000).
First report on molecular detection of equine upper respiratory infectious viruses in Republic of Korea
2013, Journal of Equine Veterinary ScienceCitation Excerpt :In the Republic of Korea (ROK), there has been one case of EHV-1 reported in an aborted fetus assayed by immunohistochemistry [21]. EHV-2 and EHV-5, differentiated from each other in 1992 [22], are Gammaherpesviruses which infect host cells but are more slowly cytopathic than Alphaherpesviruses. These viruses are widespread throughout the equine population and have been isolated from cases of respiratory disease in horses from different countries [14,23,24].
Detection of equid herpesviruses 2 and 5 in a herd of 266 Lipizzaners in association with ocular findings
2013, Veterinary MicrobiologyCitation Excerpt :Type-specific PCR assays for EHV-2, which was first isolated from a horse with respiratory disease in 1963 (Plummer and Waterson, 1963), range from 77% to 97% in blood leukocytes (Franchini et al., 1997). Fewer studies on the epidemiology of EHV-5 – which was first described in 1992 (Agius et al., 1992) – exist, however an age dependent prevalence between 20–73.3% in nasal swabs and 40–80% in blood leukocytes was determined in a study in 55 Lipizzaners (Marenzoni et al., 2010). Despite several surveys the question whether the mere infection of horses with gammaherpesviruses causes clinical symptoms still remains unsolved.
Genetic diversity of equine gammaherpesviruses (γ-EHV) and isolation of a syncytium forming EHV-2 strain from a horse in Iceland
2013, Research in Veterinary ScienceCitation Excerpt :The complete EHV-2 genome has been sequenced, and was found to be 184 kbp with 57.5% G + C and both internal and terminal repeats (Browning and Agius, 1996; Browning and Studdert, 1989; Telford et al., 1995). The genome of EHV-5 is slightly smaller, 179 kpb with similar G + C% base composition (Agius et al., 1992; Browning and Agius, 1996). Large terminal or internal repeats in the EHV-5 genome have not been reported (Agius et al., 1992).
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Sequence data from this article have been deposited with the EMBUGenBank Data Libraries under Accession No. L01473.