Original articleVascular effects of PTHrP (1–34) and PTH (1–34) in the human fetal-placental circulation
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Physiological actions of parathyroid hormone-related protein in epidermal, mammary, reproductive, and pancreatic tissues
2019, Principles of Bone BiologyPTHrP is essential for normal morphogenetic and functional development of the murine placenta
2017, Developmental BiologyCitation Excerpt :Further, PTHrP is expressed very early on in embryogenesis and involved in multiple embryonic differentiation processes including blastocyst differentiation (Karperien et al., 1994; Philbrick et al., 1996; van de Stolpe et al., 1993). Additionally, PTHrP acts as a potent vasodilator of the fetoplacental vasculature to maintain low resistance blood flow (Macgill et al., 1997) and plays an important role in the regulation of fetal calcium homeostasis and placental calcium transport (Bond et al., 2008; Kovacs et al., 1996; Tucci et al., 1996). We, and others, have previously observed that Pthlh gene ablation in mice results in dysregulated fetal growth associated with marked skeletal and limb defects (Bond et al., 2008; Karaplis et al., 1994; Kovacs et al., 2001a; Lanske and Kronenberg, 1998).
Physiological Actions of Parathyroid Hormone (PTH) and PTH-related Protein: Epidermal, Mammary, Reproductive, and Pancreatic Tissues
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2011, Fetal and Neonatal Physiology E-Book, Fourth EditionVascular, Cardiovascular, and Neurological Actions of Parathyroid-Related Protein
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2008, Principles of Bone Biology: Volume 1-2, Third Edition