Comparisons between the abilities of various human and ovine plasmas to inhibit prostaglandin synthesis

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Abstract

The ability of various human and ovine blood plasmas to inhibit prostaglandin synthesis in vitro has been tested. Human plasmas were significantly more potent in their ability to inhibit prostaglandin synthesis than their counterpart ovine plasmas. In general, female plasma had greater inhibitory activities than male plasmas and adult plasmas were more active than fetal plasmas. There was no simple correlation between the activity of plasmas as inhibitors of prostaglandin synthesis and their respective albumin or haptoglobin contents.

References (11)

  • A. Lucas et al.

    Haptoglobin, Prostaglandins and Ductus Arteriosus in Preterm Infants

    The Lancet

    (1980)
  • S.A. Saeed et al.

    Endogenous Inhibitor of Prostaglandin Synthetase

    Nature

    (1977)
  • H.O.J. Collier et al.
  • S.P. Brennecke et al.

    Prostaglandin synthesis inhibition by maternal and fetal sheep plasma and its relation to haptoglobin and albumin levels

    Prostaglandins and Medicine

    (1981)
  • J.S. Robinson et al.

    Administration of extra-amniotic arachidonic acid and the suppression of uterine prostaglandin synthesis during pregnancy in the rhesus monkey

    Journal of Reproduction & Fertility

    (1978)
There are more references available in the full text version of this article.

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