ArticleLocations and molecular forms of gastrin-releasing peptide-like immunoreactive entities in ovine pregnancy
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Interferons and progesterone for establishment and maintenance of pregnancy: Interactions among novel cell signaling pathways
2008, Reproductive BiologyCitation Excerpt :Although type I IFND and type II IFNG each induce expression of largely non-overlapping sets of genes, they may also induce synergistic interactions leading to mutual reinforcement of physiological responses [98]. This synergy has been demonstrated for cooperative induction and maintenance of expression of ISGs such as STAT1 for reinforcement of effects of distinct cell-surface ligands while maintaining their individual specificities for inducing ISGs [34, 122, 174]. Although IFNG may enhance uterine receptivity to implantation in pigs, highly localized and abundant expression of IFNG, TNFA, IL1B and IL1R in the endometrium is associated with arrested conceptus development between Days 15 and 23 of pregnancy [165].
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