Elsevier

Polyhedron

Volume 16, Issue 1, 1997, Pages 103-107
Polyhedron

Polyhedron report no. 63
Synthesis, characterization and luminiscent DNA-binding study of a series of ruthenium complexes containing 2-arylimidazo[f]1,10-phenanthroline

https://doi.org/10.1016/0277-5387(96)00232-XGet rights and content

Abstract

Starting from 1,10-phenanthroline, a series of novel ligands(L), imidazo[f]1,10-phenanthroline (IP), 2-phenylimidazo[f]1,10-phenanthroline (PIP) and the derivatives, and their complexes [Ru(bpy)2L]2+ have been synthesized and characterized. The effects of different electron donor and acceptor groups on the 1H NMR, electronic absorption and emission spectra were studied. Time-resolved luminescence studies revealed that the addition of calf thymus DNA into the complex solution results in increases for both the emissive intensities and excited state lifetimes, and indicates that the electron group on L has no significant effect on the intercalation binding mode between DNA and the complexes.

References (13)

  • A Juris et al.

    Coord. Chem. Rev.

    (1988)
  • L Wang et al.

    Inorg. Biochem.

    (1995)
  • A.M Pyle et al.

    Prog. Inorg. Chem.

    (1990)
  • R.T Morgan et al.

    Inorg. Chem.

    (1991)
  • M Eriksson et al.

    J. Am. Chem. Soc.

    (1992)
  • J.-Z Wu et al.

    Chinese Chem. Lett.

    (1995)
There are more references available in the full text version of this article.

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    The five-membered imidazole ring also reflects the purine bases in DNA. A wide variety of transition metal complexes of imidazophenanthroline with different substituents have been reported to show efficient DNA binding and nuclease activity [20–28]. Recently Xu and coworkers have reported two Cu(II) complexes which exhibit strong binding with DNA and cleaves DNA by oxidative pathway [29].

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