General Pharmacology: The Vascular System
Volume 27, Issue 4, June 1996, Pages 565-573
ReviewPharmacology of methylglyoxal: formation, modification of proteins and nucleic acids, and enzymatic detoxification-A role in pathogenesis and antiproliferative chemotherapy
References (77)
- et al.
Inhibition of proliferation of human leukemia 60 cells by methylglyoxal in vitro
Leuk. Res.
(1993) - et al.
Oxidative stress as a mediator of apoptosis
Immunol. Today
(1994) - et al.
Kinetic characteristics of Zeneca ZD5522, a potent inhibitor of human and bovine lens aldose reductase
Biochem. Pharmacol.
(1995) - et al.
Tumor-necrosis-factor and cachexia-a current perspective
Surgical Oncol.
(1994) - et al.
Induction of sister-chromatid exchanges in Chinese hamster ovary cells by the biotic ketoaldehyde methlyglyoxal
Mut. Res.
(1985) - et al.
Mechanism of protein modification by glyoxal and glycolaldehyde, reactive intermediates of the Maillard reaction
J. Biol. Chem.
(1995) - et al.
Methylglyoxal concentration and glyoxalase activities in the human lens
Exp. Eye Res.
(1994) - et al.
Identification of ethanol-inducible P-450 isozyme 3a as the acetone and acetol monoxygenase of rabbit microsomes
J. Biol. Chem.
(1985) Reactions of methylglyoxal with nucleic acids
FEBS Lett.
(1973)- et al.
Immunological comparison of glyoxalase I from yeast and mammals with quantitative determination of the enzyme in human tissues by radioimmunoassay
Comp. Biochem. Physiol.
(1985)
Inhibition of proliferation of human leukemia 60 cells by diethyl esters of glyoxalase inhibitors in vitro
Biochem. Pharmacol.
(1992)
Binding and modification of proteins by methylglyoxal under physiological conditions: a kinetic and mechanistic study with Nα-acetylarginine, Nα-acetylcysteine and Nα-acetyl-lysine, and bovine serum albumin
J. Biol. Chem.
(1994)
The reaction of methylglyoxal with aminoguanidine under physiological conditions and prevention of methylglyoxal binding to plasma proteins
Biochem. Pharmacol.
(1994)
The metabolism of aminoacetone to methylglyoxal by semicarbazide-sensitive amino oxidase in human umbilical artery
Biochem. Pharmacol.
(1992)
The assay of methylglyoxal in biological systems by derivatization with 1,2-diamino-4,5-dimethoxybenzene
Anal. Biochem.
(1992)
Quantitative determination of human aldose reductase by enzyme-linked immunosorbent assay
Biochem. Pharmacol.
(1993)
N-2 Acetylation of 2'-deoxyguanosine by coffee mutagens, methylglyoxal and hydrogen peroxide
Mutat. Res.
(1990)
Modification of the glyoxalase system in streptozotocin-induced diabetic rats: effect of the aldose reductase inhibitor Statil
Biochem. Pharmacol.
(1993)
The endothelial cell binding site for advanced glycation endproducts consists of a complex: an integral membrane protein and a lactoferrin-like polypeptide
J. Biol. Chem.
(1994)
Biologic control of the tumor-necrosis-factor and interleukin-1 signaling cascade
Amer. J. Kidney Diseases
(1995)
The glyoxalase system in health and disease
Mol. Aspects of Med.
(1993)
Advances in glyoxalase research
Anti-malarial activity of the glyoxalase I inhibitor diester, S-p-bromobenzylglutathione diethyl ester
Biochem. Pharmacol.
(1994)
Cytogenetic response to 1,2-dicarbonyls and hydrogen peroxide in Chinese hamster ovary AUXB1 cells and human peripheral lymphocytes
Mutat. Res.
(1989)
Subchronic oral toxicity of glyoxal via drinking water in rats
Fundamental Appld. Toxicol.
(1991)
D-Lactate production in erythrocytes infected with Plasmodium falciparum
Mol. Biochem. Parasitol.
(1990)
Reduction of trioses by NADPH-dependent aldo-keto reductase
J. Biol. Chem.
(1992)
Glyoxalase inhibitors as potential anticancer agents
Biochem. Biophys. Res. Comm.
(1969)
Receptor-mediated endocytic uptake of methylglyoxal-modified protein
A simplified method for the purification of human red blood cell glyoxalase I. Characteristics, immunoblotting and inhibitor studies
J. Protein Chem.
(1993)
Macrophage scavenger receptor mediates endocytic uptake and degradation of advanced glycation end products of the Maillard reaction
Eur. J. Biochem.
(1995)
Methylglyoxal-induced DNA-protein crosslinks and cytotoxicity in Chinese hamster ovary cells
Carcinogenesis
(1985)
Aminoguanidine prevents diabetes-induced arterial wall protein cross-linking
Science
(1986)
Effects of aminoguanidine on peripheral nerve function and polyol pathway metabolites in streptozotocin-diabetic rats
Diabetologia
(1992)
Optimization of efficiency in the glyoxalase pathway
Biochemistry
(1988)
Glomerular macrophages and the mesangial proliferative response in experimental nephrotic syndrome
Amer. J. Pathol.
(1992)
Nutritional and physiological consequences of tumor glycolysis
Parasitology
(1993)
Aldose reductase: model for a new paradigm of enzymic perfection in detoxification catalysts
Biochemistry
(1992)
Cited by (540)
Glyoxalase I is a novel target for the prevention of metabolic derangement
2023, Pharmacology and TherapeuticsFunction and therapeutic value of astrocytes in diabetic cognitive impairment
2023, Neurochemistry InternationalDietary modulation of advanced glycation end products metabolism on carotid intima-media thickness in type 2 diabetes patients: From the CORDIOPREV study
2023, Clinica e Investigacion en ArteriosclerosisThe expanding impact of methylglyoxal on behavior-related disorders
2023, Progress in Neuro-Psychopharmacology and Biological PsychiatryModulators of a robust and efficient metabolism: Perspective and insights from the Rid superfamily of proteins
2023, Advances in Microbial Physiology
Copyright © 1996 Published by Elsevier Inc.