5-Hydroxytryptamine1 recognition sites in rat brain: Heterogeneity of non-5-hydroxytryptamine1a/1c binding sites revealed by quantitative receptor autoradiography
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Cited by (32)
Serotonin modulation of the basal ganglia circuitry: therapeutic implication for Parkinson's disease and other motor disorders
2008, Progress in Brain ResearchCitation Excerpt :Similarly to 5-HT1B receptors, some authors described a discrepancy in the distribution pattern of 5-HT1D mRNA and its protein in the striatum, SN and GP of mouse brain and therefore hypothesized a presynaptic localization of 5-HT1D receptors in the latter two areas (Boschert et al., 1994). Finally, regarding the 5-HT1 receptor family, Bruinvels et al. (1993b) reported the presence of the 5-HT1E receptor subtype mRNA in both the caudate nucleus and putamen of primates, showing stronger hybridization signals in monkey brain than that obtained in human brain. Both 5-HT2A receptor subtype and its mRNA have been extensively demonstrated to be present in the striatum of various mammal species.
Serotonin and the Orchestration of Energy Balance
2007, Cell MetabolismCitation Excerpt :Through widespread projections to regions that include the hypothalamus, amygdala, and brainstem, it participates in the regulation of feeding, drinking, respiration, and cardiovascular function (Saper and Loewy, 1980). The PBN receives serotonergic innervation from the dorsal raphe nucleus and area postrema (Petrov et al., 1992; Simansky and Nicklous, 2002) and expresses both 5-HT2CRs and 5-HT1BRs (Bruinvels et al., 1993; Wright et al., 1995). An important contribution of the PBN to dFen-induced anorexia is indicated by the ability of PBN lesions to suppress this effect (Li et al., 1994).
5-HT-1E receptor
2007, xPharm: The Comprehensive Pharmacology ReferenceCentral 5-HT<inf>1</inf> and 5-HT<inf>2</inf> binding sites in transgenic mice with reduced glucocorticoid receptor number
2000, Brain ResearchCitation Excerpt :Other sections were treated the same way but incubated in the presence of 2 nM [3H]5-HT, added with 100 nM 8-OH-DPAT and 100 nM mesulergine which prevent the labelling of 5-HT1A and 5-HT2C sites, respectively. This way, all 5-HT1nonA sites were labelled, i.e. 5-HT1B, 5-HT1D, 5-HT1E and 5-HT1F subtypes, although in mice and rats 5-HT1B are predominant in most structures [8]. These sections were then rinsed 3×20-s, dried and exposed for about 1 month.
A review of central 5-HT receptors and their function
1999, Neuropharmacology
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Present address: Departemento de Neuroquimica, C.I.D., C.S.I.C., Jordi Girona 18-26, Barcelona 08034, Spain.