Active tyrosine phosphatase in immunoprecipitates of multiple isoforms of Ly-5

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Abstract

Using tumour cell lines expressing specific isoforms of murine Ly-5 (molecular weights of 180,000, 200,000 and 240,000) we find that all forms of Ly-5 and immuno-affinity purified forms of Ly-5 contain tyrosyl phosphatase activity. These results demonstrate that these isoforms of Ly-5 belong to the same family of functional receptor-linked tyrosine phosphatases as the human leukocyte common antigen, CD45.

References (12)

  • N.K. Tonks et al.

    J. biol. Chem.

    (1988)
  • M.L. Thomas et al.

    Cell

    (1985)
  • H. Charbonneau et al.
  • M.L. Tonks et al.

    Biochemistry

    (1988)
  • K. Komuro et al.

    Immunogenetics

    (1975)
  • C. House et al.

    Eur. J. Biochem.

    (1984)
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