Steroid peptide interaction in the central nervous systemSteroid control of central neuronal interactions and function
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A users guide to HPA axis research
2017, Physiology and BehaviorCitation Excerpt :It is less clear to what extent these neurons are necessary for circadian variation in basal CORT secretion [47]. These neurons are also directly regulated by glucocorticoids and are a primary site of action for glucocorticoid negative feedback [4,54–56]. Because only very small quantities of CRF are released in the median eminence, hypophysiotropic CRF levels cannot be measured in the systemic circulation.
Molecular Biology and Gene Regulation
2017, Textbook of Nephro-EndocrinologyNeural control of the anterior lobe of the pituitary gland (Pars Distalis)
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2011, Journal of Psychiatric ResearchCitation Excerpt :These data show other effects of ouabain in addition to its actions on the GR-α and GR-β mRNA levels, probably reflecting more profound actions on cellular structures and metabolism. Since GRs play an important role in the regulation of endocrine and central nervous system functions (Fink et al., 1991), the aim of the present study was to consolidate the hypothesis that Hypericum exerts its clinical efficacy via normalization of HPA-activity due to a differential modulation of GR functions. Therefore, this approach included an examination of the different forms of GRs, i. e. the GR-α and the GR-β.
The endocrine nervous system: Source and target for neuroactive steroids
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