Review
Enzymatic catalysis in anhydrous organic solvents

https://doi.org/10.1016/0968-0004(89)90146-1Get rights and content

Abstract

Not only do enzymes work vigorously in anhydrous organic media, but in this unnatural milieu they acquire remarkable properties such as greatly enhanced stability, radically altered substrate and enantiomeric specificities, molecular memory, and the ability to catalyse unusual reactions.

References (28)

  • J.A. Rupley et al.

    Trends Biochem. Sci.

    (1983)
  • A. Zaks et al.

    J. Biol. Chem.

    (1988)
  • A. Zaks et al.

    J. Biol. Chem.

    (1988)
  • A.J. Russell et al.

    J. Biol. Chem.

    (1988)
  • A.J. Russell et al.

    Biochem. Biophys. Res. Commun.

    (1989)
  • A. Fersht

    Enzyme Structure and Mechanism

    (1985)
  • A.M. Klibanov

    Chemtech.

    (1986)
  • E. Bourquelot et al.

    J. Pharm. Chim.

    (1911)
  • K. Martinek et al.

    Eur. J. Biochem.

    (1986)
  • C.R. Cantor et al.

    Biophysical Chemistry, Part I

    (1980)
  • T.E. Creighton

    Proteins: Structure and Molecular Properties

    (1983)
  • A. Zaks et al.
  • C. Laane et al.

    Biotechnol. Bioeng.

    (1987)
  • S.J. Singer

    Adv. Protein Chem.

    (1962)
  • Cited by (816)

    View all citing articles on Scopus
    View full text