On target with a new mechanism for the regulation of protein phosphorylation

doi:10.1016/0968-0004(93)90109-Z

Trends in Biochemical Sciences

Volume 18, Issue 5, May 1993, Pages 172-177

https://doi.org/10.1016/0968-0004(93)90109-Z Get rights and content

Abstract

There is overwhelming evidence that the reversible phosphorylation of proteins regulates most aspects of cell life. However, the broad specificities displayed by many protein phosphatases and kinases in vitro dictates that their activities be strictly regulated in vivo. Recent evidence indicates that a novel class of proteins, known as targetting subunits, specifies the location, catalytic and regulatory properties of protein phosphatases and kinases, and thereby plays a key role in ensuring the fidelity of protein phosphorylation.

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Trends in Biochemical Sciences

On target with a new mechanism for the regulation of protein phosphorylation

Abstract

J. Biol. Chem.

J. Biol. Chem.

J. Biol. Chem.

Curr. Biol.

J. Biol. Chem.

J. Biol. Chem.

Trends Cell Biol.

Trends Biochem. Sci.

Cell

Cell

Cell

J. Biol. Chem.

J. Biol. Chem.

Ann. Rev. Biochem.

Eur. J. Biochem.

Eur. J. Biochem.

Eur. J. Biochem.

Eur. J. Biochem.

Eur. J. Biochem.

FEBS Lett.