Functional imagingClinical applications of fusion imaging in oncology
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Comparison of diffusion tensor, dynamic susceptibility contrast MRI and <sup>99m</sup>Tc-Tetrofosmin brain SPECT for the detection of recurrent high-grade glioma
2014, Magnetic Resonance ImagingCitation Excerpt :In addition, the location of the lesion may also influence the diagnostic performance. In SPECT imaging, infratentorial lesions tend to display lower tracer uptake [26]. The present study has several limitations.
Brain and Spinal Cord
2013, Clinical Imaging: With Skeletal, Chest, & Abdominal Pattern Differentials: Third EditionPositron emission tomography/magnetic resonance: Present and future
2013, Revista Espanola de Medicina Nuclear e Imagen MolecularSingle-Photon Emission Computed Tomography/Computed Tomography in Brain Tumors
2007, Seminars in Nuclear MedicineCitation Excerpt :Compared with conventional neuroimaging, 201Tl SPECT added valuable information in the assessment of the response to chemotherapy (plus radiotherapy in some cases), especially when findings were not conclusive and in the case of disagreement between CT and MRI outcomes.36 Image registration and fusion with anatomical images have many potential applications during the clinical workup of brain tumors patients studied with 201Tl imaging because 201Tl does not accumulate in normal brain parenchyma, and so the anatomical localization is difficult.37 Until now, physicians have relied principally on their spatial sense to mentally reorient and overlap 201Tl images with the anatomic data: this approach is inconsistent and highly subjective and can yield suboptimal results because it does not take full advantage of all the information available.38
Single-Photon Emission Computed Tomography/Computed Tomography in Abdominal Diseases
2007, Seminars in Nuclear MedicineCitation Excerpt :In a series including 37 patients with 69 suspected hemangiomas found by CT and/or US, 99mTc RBC SPECT did not demonstrate 6 of 18 hemangiomas adjacent to major intrahepatic vessels, or at the hepatic dome near the heart and/or the confluence of the hepatic veins.24 The problems related to lesions’ site can be addressed by the use of fusion techniques that allow accurate anatomic localization of foci of increased activity.23 Birnbaum and coworkers25 fused 99mTc-labeled-RBC SPECT with CT and MRI to evaluate the role of functional-anatomical images in characterizing liver tissue.
SPECT/CT in tumor imaging: Technical aspects and clinical applications
2003, Seminars in Nuclear MedicineCitation Excerpt :Coregistration and hybrid SPECT/CT imaging, by precisely localizing Ga67-uptake, has the potential to improve lymphoma lesion detectability and to characterize physiologic, benign, or equivocal lesions. Coregistration of Ga67-SPECT with CT or MRI has been used for exact definition of nonspecific Ga67-uptake in the hilar region and for identification of a residual retrosternal tumor in the anterior mediastinum masked by normal bone uptake.89 Lymphomatous lesions located in the bone could be discriminated from soft tissue involvement adjacent to skeletal structures and have enabled the differentiation of physiological bowel uptake from lymphoma.