Chapter 9 - Molybdenum Requirements, Toxicity and Nutritional Limits for Man and Animals

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  • Cited by (22)

    • Potential elemental exposure and health risk associated with the consumption of groundnut paste processed with local milling machines within the Kumasi metropolis

      2021, Scientific African
      Citation Excerpt :

      Molybdenum forms the catalytic center of a large variety of enzymes such as nitrogenase, nitrate reductases, sulphite oxidase and xanthine oxidoreductases [29]. High levels of molybdenum can cause kidney problems and copper deficiencies due to the mechanism of molybdenum-copper antagonism [35]. The relatively high levels of these essential elements can however cause some health problems.

    • Water Quality for Cattle: Metalloid and Metal Contamination of Water

      2020, Veterinary Clinics of North America - Food Animal Practice
      Citation Excerpt :

      Mo is essential for mammals as a cofactor in aldehyde oxidase, sulfite oxidase, and xanthine oxidase,185,198 where it is responsible for catalyzing the oxidation or metabolism of sulfur (S)-containing amino acids, purines, pyrimidines, and aldehydes. Dietary requirements are so low (about 100 ppb dry matter); however, that deficiency is very rare under natural conditions.198 Once ingested, Mo is absorbed in the stomach and throughout the small intestine.

    • A two-generation reproductive toxicity study of sodium molybdate dihydrate administered in drinking water or diet to Sprague-Dawley rats

      2019, Reproductive Toxicology
      Citation Excerpt :

      Occupational exposure to Mo may also occur from mining and industrial processes, such as the manufacture of structural steel and stainless steel. The toxicity of excessive dietary exposure to Mo is well known in cattle and sheep, causing a condition known as “teart” or molybdenosis, which is characterized by diarrhea, weight loss, discolored coats, and ultimately death if not treated [3]. This condition in cattle and sheep is associated with reduced bioavailability of copper (Cu) due to high levels of sulfide in the rumen that interacts with molybdate to form thiomolybdates [4].

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